Human Ubiquitin/ISG15-conjugating enzyme E2 L6, UBE2L6 ELISA Kit | MyBioSource MBS9321948 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Ubiquitin/ISG15-conjugating enzyme E2 L6, UBE2L6 ELISA Kit

catalog :

MBS9321948

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9321948

products type :

ELISA Kit

products full name :

Human Ubiquitin/ISG15-conjugating enzyme E2 L6, UBE2L6 ELISA Kit

products short name :

[ubiquitin-conjugating enzyme E2L 6]

products name syn :

[Human Ubiquitin/ISG15-conjugating enzyme E2 L6 (UBE2L6) ELISA kit; MGC40331; RIG-B; UBCH8; retinoic acid induced gene B protein; ubiquitin carrier protein; ubiquitin-protein ligase; ubiquitin-conjugating enzyme E2L 6]

other names :

[ubiquitin/ISG15-conjugating enzyme E2 L6 isoform 1; Ubiquitin/ISG15-conjugating enzyme E2 L6; ubiquitin/ISG15-conjugating enzyme E2 L6; ubiquitin-protein ligase L6; ubiquitin carrier protein L6; retinoic acid induced gene B protein; retinoic acid-induced gene B protein; ubiquitin-conjugating enzyme E2L 6; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6]

products gene name :

[UBE2L6]

other gene names :

[UBE2L6; UBE2L6; RIG-B; UBCH8; UBCH8; RIG-B]

uniprot entry name :

UB2L6_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of UBE2L6 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

4759282

ncbi acc num :

NP_004214.1

ncbi gb acc num :

NM_004223.4

uniprot acc num :

O14933

ncbi mol weight :

17,769 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Antigen Processing: Ubiquitination Proteasome Degradation Pathway (366162); Antiviral Mechanism By IFN-stimulated Genes Pathway (530760); Class I MHC Mediated Antigen Processing Presentation Pathway (366161); Cytokine Signaling In Immune System Pathway (366171); ISG15 Antiviral Mechanism Pathway (530761); Immune System Pathway (106386); Innate Immune System Pathway (106387); Interferon Signaling Pathway (187103); Negative Regulators Of RIG-I/MDA5 Signaling Pathway (187102)

ncbi summary :

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011]

uniprot summary :

UBE2L6: Catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Promotes ubiquitination and subsequent proteasomal degradation of FLT3. Belongs to the ubiquitin-conjugating enzyme family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 6.3.2.19; Ligase; Ubiquitin ligase; Ubiquitin conjugating system. Chromosomal Location of Human Ortholog: 11q12. Cellular Component: cytosol. Molecular Function: protein binding; ISG15 conjugating enzyme activity; ubiquitin-protein ligase activity; ligase activity. Biological Process: modification-dependent protein catabolic process; ISG15-protein conjugation; cytokine and chemokine mediated signaling pathway; innate immune response; protein modification process; protein ubiquitination; negative regulation of interferon type I production

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage