ELISA/assay

Mouse Histone-lysine N-methyltransferase EHMT2, EHMT2 ELISA Kit

MBS9321826

48-Strip-Wells

470 USD

ELISA Kit

Mouse Histone-lysine N-methyltransferase EHMT2, EHMT2 ELISA Kit

[euchromatic histone-lysine N-methyltransferase 2]

[Mouse Histone-lysine N-methyltransferase EHMT2 (EHMT2) ELISA kit; DAAP-66K18.3; BAT8; C6orf30; DKFZp686H08213; FLJ35547; G9A; KMT1C; NG36; G9A histone methyltransferase; H3-K9-HMTase 3; HLA-B associated transcript 8; ankyrin repeat-containing protein; histone H3-K9 me; euchromatic histone-lysine N-methyltransferase 2]

[histone-lysine N-methyltransferase EHMT2 isoform c; Histone-lysine N-methyltransferase EHMT2; histone-lysine N-methyltransferase EHMT2; protein G9a; H3-K9-HMTase 3; HLA-B associated transcript 8; HLA-B-associated transcript 8; histone H3-K9 methyltransferase 3; euchromatic histone-lysine N-methyltransferase 2; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; euchromatic histone lysine N-methyltransferase 2; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Protein G9a]

[EHMT2]

[Ehmt2; Ehmt2; G9a; Bat8; NG36; KMT1C; D17Ertd710e; Bat8; G9a; Ng36; H3-K9-HMTase 3]

EHMT2_MOUSE

Mouse

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EHMT2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

557440749

NP_001273502.1

NM_001286573.1

Q9Z148

138,039 Da

Cellular Senescence Pathway (971023); Cellular Responses To Stress Pathway (971022); Gene Expression Pathway (971427); Histone Modifications Pathway (198313); Lysine Degradation Pathway (83156); Lysine Degradation Pathway (320); One Carbon Metabolism Pathway (198340); PluriNetWork Pathway (198307); RNA Polymerase I Promoter Clearance Pathway (970736); RNA Polymerase I Transcription Pathway (971450)

EHMT2: Histone methyltransferase. Preferentially methylates Lys-9 of histone H3 and Lys-27 of histone H3 (in vitro). H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. Also methylates histone H1. Belongs to the histone-lysine methyltransferase family. Suvar3-9 subfamily. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts with GFI1B, WIZ and EHMT1. 3 isoforms of the human protein are produced by alternative splicing. Protein type: EC 2.1.1.43; Amino Acid Metabolism - lysine degradation; Methyltransferase, protein lysine; Methyltransferase. Cellular Component: nucleoplasm; intermediate filament cytoskeleton; intracellular membrane-bound organelle; nuclear chromatin; nucleolus; chromosome; nucleus. Molecular Function: methyltransferase activity; trimethylamine methyltransferase activity; monomethylamine methyltransferase activity; RNA methyltransferase activity; tRNA (cytosine)-methyltransferase activity; rRNA (cytosine-C5-967)-methyltransferase activity; rRNA (uridine) methyltransferase activity; N-methyltransferase activity; histone-lysine N-methyltransferase activity; tRNA (guanine) methyltransferase activity; histone lysine N-methyltransferase activity (H3-K27 specific); rRNA (adenine-N6,N6-)-dimethyltransferase activity; arginine N-methyltransferase activity; selenocysteine methyltransferase activity; methanol-specific methylcobalamin:coenzyme M methyltransferase activity; protein-arginine N-methyltransferase activity; tRNA (guanine-N2-)-methyltransferase activity; dimethylamine methyltransferase activity; protein methyltransferase activity; 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity; transferase activity; hydroxyneurosporene-O-methyltransferase activity; rRNA (uridine-2 -O-)-methyltransferase activity; tRNA (uracil) methyltransferase activity; rRNA (adenine) methyltransferase activity; histone lysine N-methyltransferase activity (H3-K9 specific); C-methyltransferase activity; cobalt-precorrin-6B C5-methyltransferase activity; cobalt-precorrin-3 C17-methyltransferase activity; 1-phenanthrol methyltransferase activity; zinc ion binding; metal ion binding; S-methyltransferase activity; lysine N-methyltransferase activity; DNA-methyltransferase activity; tRNA (cytosine-5-)-methyltransferase activity; C-terminal protein carboxyl methyltransferase activity; tRNA (adenine)-methyltransferase activity; rRNA (cytosine) methyltransferase activity; cobalt-precorrin-7 C15-methyltransferase activity; protein-arginine N5-methyltransferase activity; rRNA methyltransferase activity; p53 binding; protein-leucine O-methyltransferase activity; demethylmenaquinone methyltransferase activity; rRNA (adenine-N6-)-methyltransferase activity; tRNA methyltransferase activity; rRNA (guanine) methyltransferase activity; methylarsonite methyltransferase activity; protein binding; mRNA methyltransferase activity; methylamine-specific methylcobalamin:coenzyme M methyltransferase activity; tRNA (guanine-N1-)-methyltransferase activity; cobalt-precorrin-5B C1-methyltransferase activity; protein-lysine N-methyltransferase activity; O-methyltransferase activity; tRNA (adenine-N1-)-methyltransferase activity; tRNA (adenine-57, 58-N(1)-) methyltransferase activity. Biological Process: methylation; synaptonemal complex assembly; negative regulation of transcription from RNA polymerase II promoter; chromatin modification; germ cell development; peptidyl-lysine methylation; regulation of transcription from RNA polymerase II promoter; histone methylation; organ growth; cytosine methylation within a CG sequence; fertilization; long-term memory; peptidyl-lysine di-methylation; DNA methylation; regulation of histone H3-K4 methylation; regulation of histone H3-K9 methylation; spermatid development; histone H3-K9 methylation; regulation of DNA replication

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095