ELISA/assay

Human Transducin-like enhancer protein 3, TLE3 ELISA Kit

MBS9321521

48-Strip-Wells

470 USD

ELISA Kit

Human Transducin-like enhancer protein 3, TLE3 ELISA Kit

[transducin-like enhancer of split 3 (E (sp1) homolog, Drosophila)]

[Human Transducin-like enhancer protein 3 (TLE3) ELISA kit; ESG; ESG3; FLJ39460; GRG3; HsT18976; KIAA1547; enhancer of split groucho 3; transducin-like enhancer of split 3; homolog of Drosophila E (sp1) ; transducin-like enhancer protein 3; transducin-like enhancer of split 3 (E (sp1) homolog; Drosophila)]

[transducin-like enhancer protein 3 isoform b; Transducin-like enhancer protein 3; transducin-like enhancer protein 3; enhancer of split groucho 3; enhancer of split groucho-like protein 3; transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 3, homolog of Drosophila E(sp1); transducin-like enhancer of split 3; Enhancer of split groucho-like protein 3; ESG3]

[TLE3]

[TLE3; TLE3; ESG; ESG3; GRG3; HsT18976; KIAA1547; ESG3]

TLE3_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TLE3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

157384986

NP_001098662.1

NM_001105192.2

Q04726

82,279 Da

NOTCH1 Intracellular Domain Regulates Transcription Pathway (576271); Signal Transduction Pathway (477114); Signaling By NOTCH Pathway (106485); Signaling By NOTCH1 Pathway (576269)

This gene encodes a transcriptional co-repressor protein that belongs to the transducin-like enhancer family of proteins. The members of this family function in the Notch signaling pathway that regulates determination of cell fate during development. Expression of this gene has been associated with a favorable outcome to chemotherapy with taxanes for ovarian carcinoma. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]

TLE3: transcriptional corepressor that binds to a number of transcription factors. Belongs to the WD-repeat Groucho/TLE family. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Four alternatively spliced isoforms have been described. Protein type: Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 15q22. Cellular Component: nucleoplasm; nucleus. Molecular Function: protein binding. Biological Process: Notch signaling pathway; organ morphogenesis; Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; signal transduction

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095