catalog number :
MBS9321322
products type :
ELISA Kit
products full name :
Human Ephrin type-A receptor 7, EPHA7 ELISA Kit
products short name :
[EPH receptor A7]
products name syn :
[Human Ephrin type-A receptor 7 (EPHA7) ELISA kit; EHK3; HEK11; Eph homology kinase-3; ephrin receptor EphA7; ephrin type-A receptor 7; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; EPH receptor A7]
other names :
[ephrin type-A receptor 7 isoform 2; Ephrin type-A receptor 7; ephrin type-A receptor 7; EPH-like kinase 11; EPH homology kinase 3; Eph homology kinase-3; receptor protein-tyrosine kinase HEK11; tyrosine-protein kinase receptor EHK-3; EPH receptor A7; EPH homology kinase 3; EHK-3; EPH-like kinase 11; EK11; hEK11]
products gene name :
[EPHA7]
other gene names :
[EPHA7; EPHA7; EHK3; EK11; EHK-3; HEK11; EHK3; HEK11; EHK-3; EK11; hEK11]
uniprot entry name :
EPHA7_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of EPHA4 (hereafter termed "analyte") in undiluted original Mouse serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001275558.1
ncbi gb acc num :
NM_001288629.1
ncbi mol weight :
112,097 Da
ncbi pathways :
Axon Guidance Pathway (83065); Axon Guidance Pathway (476); EPHA Forward Signaling Pathway (138041); EphrinA-EPHA Pathway (137942)
ncbi summary :
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
uniprot summary :
EphA7: a widely-expressed receptor tyrosine kinase of the Eph family. Receptor for members of the ephrin-A family. Binds to ephrin-A1, -A2, -A3, -A4 and -A5. Contains 1 sterile alpha motif (SAM) and two fibronectin type III domains. Protein type: EC 2.7.10.1; Protein kinase, TK; Kinase, protein; Protein kinase, tyrosine (receptor); Membrane protein, integral; TK group; Eph family. Chromosomal Location of Human Ortholog: 6q16.1. Cellular Component: postsynaptic membrane; cell soma; integral to plasma membrane; dendrite; plasma membrane; neuromuscular junction. Molecular Function: protein binding; ephrin receptor binding; GPI-linked ephrin receptor activity; chemorepellent activity; protein-tyrosine kinase activity; axon guidance receptor activity; ATP binding. Biological Process: axon guidance; peptidyl-tyrosine phosphorylation; regulation of cell-cell adhesion; branching morphogenesis of a nerve; positive regulation of neuron apoptosis; regulation of protein amino acid autophosphorylation; ephrin receptor signaling pathway; negative chemotaxis; brain development; regulation of caspase activity; phosphorylation; regulation of peptidyl-tyrosine phosphorylation; retinal ganglion cell axon guidance
size4 :
10x96-Strip-Wells