This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Engulfment and cell motility protein 1, ELMO1 ELISA Kit
catalog :
MBS9321199
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS9321199
products type :
ELISA Kit
products full name :
Human Engulfment and cell motility protein 1, ELMO1 ELISA Kit
products short name :
[engulfment and cell motility 1]
products name syn :
[Human Engulfment and cell motility protein 1 (ELMO1) ELISA kit; CED-12; CED12; ELMO-1; KIAA0281; MGC126406; OTTHUMP00000207056; OTTHUMP00000207060; ced-12 homolog 1; engulfment and cell motility 1]
other names :
[engulfment and cell motility protein 1 isoform 2; Engulfment and cell motility protein 1; engulfment and cell motility protein 1; ced-12 homolog 1; engulfment and cell motility 1; Protein ced-12 homolog]
products gene name :
[ELMO1]
other gene names :
[ELMO1; ELMO1; CED12; CED-12; ELMO-1; KIAA0281]
uniprot entry name :
ELMO1_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ELMO1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
86788140
ncbi acc num :
NP_001034548.1
ncbi gb acc num :
NM_001039459.2
uniprot acc num :
Q92556
ncbi mol weight :
83,829 Da
ncbi pathways :
Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); Chemokine Signaling Pathway (99051); Chemokine Signaling Pathway (96864); Disease Pathway (530764); HIV Infection Pathway (105983); Host Interactions Of HIV Factors Pathway (106010); Nef And Signal Transduction Pathway (106020); Neurotrophic Factor-mediated Trk Receptor Signaling Pathway (137977); Regulation Of RAC1 Activity Pathway (169346)
ncbi summary :
This gene encodes a member of the engulfment and cell motility protein family. These proteins interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
uniprot summary :
ELMO1: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 7p14.1. Cellular Component: cytoskeleton; membrane; cytoplasm; plasma membrane; cytosol. Molecular Function: protein binding; SH3 domain binding. Biological Process: viral reproduction; apoptosis; Rac protein signal transduction; innate immune response; vascular endothelial growth factor receptor signaling pathway; cell motility; phagocytosis, engulfment; actin cytoskeleton organization and biogenesis; regulation of defense response to virus by virus
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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