catalog number :
MBS9320977
products type :
ELISA Kit
products full name :
Human Junctional adhesion molecule-like, AMICA1 ELISA Kit
products short name :
adhesion molecule, interacts with CXADR antigen 1
products name syn :
Human Junctional adhesion molecule-like (AMICA1) ELISA kit; AMICA; CREA7-1; CREA7-4; FLJ37080; Gm638; JAML; MGC118814; MGC118815; adhesion molecule AMICA; adhesion molecule that interacts with CXADR antigen 1; dendritic-cell specific protein CREA7-1; dendritic-; adhesion molecule; interacts with CXADR antigen 1
other names :
junctional adhesion molecule-like isoform 1; Junctional adhesion molecule-like; junctional adhesion molecule-like; adhesion molecule AMICA; dendritic-cell specific protein CREA7-1; dendritic-cell specific protein CREA7-4; adhesion molecule interacting with CXADR antigen 1; adhesion molecule, interacts with CXADR antigen 1; Adhesion molecule interacting with CXADR antigen 1; Dendritic cell-specific protein CREA7-1
products gene name :
AMICA1
other gene names :
AMICA1; AMICA1; JAML; AMICA; Gm638; CREA7-1; CREA7-4; JAML; UNQ722/PRO1387
uniprot entry name :
JAML1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of AMICA1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001091996.1
ncbi gb acc num :
NM_001098526.1
ncbi mol weight :
40,136 Da
ncbi pathways :
Adaptive Immune System Pathway (366160); Cell Surface Interactions At The Vascular Wall Pathway (106062); Hemostasis Pathway (106028); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413); Integrin Cell Surface Interactions Pathway (106110); Signal Transduction Pathway (477114)
uniprot summary :
AMICA1: an adhesion molecule that may function in the migration of leukocytes through epithelial and endothelial tissues. Expressed at the plasma membrane of polymorphonuclear leukocytes, it mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells. Enhances myeloid leukemia cell adhesion to endothelial cells. Up-regulated upon retinoic acid, Me2SO and PMA treatment in differentiating myeloid leukemia cells. Three alternatively spliced isoforms have been described. Protein type: Membrane protein, integral; Cell adhesion. Chromosomal Location of Human Ortholog: 11q23.3. Cellular Component: tight junction; integral to membrane; plasma membrane. Molecular Function: integrin binding; protein homodimerization activity; cell adhesion molecule binding. Biological Process: heterophilic cell adhesion; neutrophil chemotaxis; regulation of immune response; positive regulation of epithelial cell proliferation involved in wound healing; blood coagulation; gamma-delta T cell activation; leukocyte migration