catalog number :
MBS9320902
products type :
ELISA Kit
products full name :
Human N (4) - (beta-N-acetylglucosaminyl) -L-asparaginase, AGA ELISA Kit
products short name :
[aspartylglucosaminidase]
products name syn :
[Human N (4) - (beta-N-acetylglucosaminyl) -L-asparaginase (AGA) ELISA kit; AGU; ASRG; GA; N (4) - (beta-N-acetylglucosaminyl) -L-asparaginase; N4- (N-acetyl-beta-glucosaminyl) -L-asparagine amidase; aspartylglucosylamine deaspartylase; glycosylasparaginase; aspartylglucosaminidase]
other names :
[N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase isoform 1 preproprotein; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase; glycosylasparaginase; aspartylglucosylamine deaspartylase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidase; aspartylglucosaminidase; Aspartylglucosaminidase; Glycosylasparaginase; N4-(N-acetyl-beta-glucosaminyl)-L-asparagine amidaseCleaved into the following 2 chains:Glycosylasparaginase alpha chain; Glycosylasparaginase beta chain]
products gene name :
[AGA]
other gene names :
[AGA; AGA; GA; AGU; ASRG]
uniprot entry name :
ASPG_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of AGA (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_000018.2
ncbi gb acc num :
NM_000027.3
ncbi mol weight :
37,208 Da
ncbi pathways :
Lysosome Pathway (99052); Lysosome Pathway (96865); Other Glycan Degradation Pathway (82976); Other Glycan Degradation Pathway (346)
ncbi summary :
Aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. Alternatively spliced transcript variants have been identified. [provided by RefSeq, Jan 2010]
uniprot summary :
AGA: a catabolic enzyme, aspartylglucosaminidase is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. The lysosomal storage disease aspartylglycosaminuria is caused by a deficiency in the AGA enzyme. Protein type: Hydrolase; EC 3.5.1.26; Glycan Metabolism - other glycan degradation. Chromosomal Location of Human Ortholog: 4q34.3. Cellular Component: endoplasmic reticulum; lysosome. Molecular Function: peptidase activity; protein self-association; N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity. Biological Process: protein maturation; protein deglycosylation; proteolysis. Disease: Aspartylglucosaminuria
size4 :
10x96-Strip-Wells