catalog number :
MBS9320819
products type :
ELISA Kit
products full name :
Human Growth arrest-specific protein 1, GAS1 ELISA Kit
products short name :
[growth arrest-specific 1]
products name syn :
[Human Growth arrest-specific protein 1 (GAS1) ELISA kit; Growth arrest-specific gene-1; growth arrest-specific 1]
other names :
[growth arrest-specific protein 1; Growth arrest-specific protein 1; growth arrest-specific protein 1; GAS-1; Growth arrest-specific gene-1; growth arrest-specific 1]
products gene name :
[GAS1]
other gene names :
[GAS1; GAS1; GAS-1]
uniprot entry name :
GAS1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GAS1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_002039.2
ncbi gb acc num :
NM_002048.2
ncbi mol weight :
35,693 Da
ncbi pathways :
FOXM1 Transcription Factor Network Pathway (137935); Hedgehog Signaling Pathway (198835); Hedgehog Signaling Pathway (83063); Hedgehog Signaling Pathway (474); Signaling Events Mediated By The Hedgehog Family Pathway (137950)
ncbi summary :
Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008]
uniprot summary :
GAS1: Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 9q21.3-q22. Cellular Component: anchored to plasma membrane; integral to membrane; plasma membrane. Molecular Function: protein binding. Biological Process: developmental growth; axon guidance; cell fate commitment; camera-type eye development; outer ear morphogenesis; programmed cell death; cerebellum morphogenesis; embryonic cranial skeleton morphogenesis; palate development; middle ear morphogenesis; regulation of apoptosis; odontogenesis; negative regulation of smoothened signaling pathway; positive regulation of mesenchymal cell proliferation; positive regulation of smoothened signaling pathway; negative regulation of mitotic cell cycle; negative regulation of cell growth; embryonic digit morphogenesis; cell cycle arrest; positive regulation of epithelial cell proliferation; dorsoventral neural tube patterning; regulation of smoothened signaling pathway; eye morphogenesis; negative regulation of epithelial cell proliferation
size4 :
10x96-Strip-Wells