product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human T-lymphoma invasion and metastasis-inducing protein 2, TIAM2 ELISA Kit
catalog :
MBS9320560
quantity :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9320560
products type :
ELISA Kit
products full name :
Human T-lymphoma invasion and metastasis-inducing protein 2, TIAM2 ELISA Kit
products short name :
T-cell lymphoma invasion and metastasis 2
products name syn :
Human T-lymphoma invasion and metastasis-inducing protein 2 (TIAM2) ELISA kit; RP3-414L4.2; FLJ41865; STEF; SIF and TIAM1-like exchange factor; T-cell lymphoma invasion and metastasis 2
other names :
T-lymphoma invasion and metastasis-inducing protein 2 isoform b; T-lymphoma invasion and metastasis-inducing protein 2; T-lymphoma invasion and metastasis-inducing protein 2; SIF and TIAM1-like exchange factor; T-cell lymphoma invasion and metastasis 2; SIF and TIAM1-like exchange factor
products gene name :
TIAM2
other gene names :
TIAM2; TIAM2; STEF; TIAM-2; KIAA2016; STEF; TIAM-2
uniprot entry name :
TIAM2_HUMAN
reactivity :
Human
ncbi gi num :
58331189
ncbi acc num :
NP_001010927.1
ncbi gb acc num :
NM_001010927.2
uniprot acc num :
Q8IVF5
ncbi mol weight :
190,103 Da
ncbi pathways :
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway 106443!!Chemokine Signaling Pathway 99051!!Chemokine Signaling Pathway 96864!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!G Alpha (12/13) Signalling Events Pathway 106041!!GPCR Downstream Signaling Pathway 119548!!Metabolism Pathway 477135!!Metabolism Of Lipids And Lipoproteins Pathway 160976!!NRAGE Signals Death Through JNK Pathway 106444!!PPARA Activates Gene Expression Pathway 530749
ncbi summary :
This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane Activates specifically RAC1, but not CDC42 and RHOA.1 PublicationManual assertion based on experiment in:Ref.1
size :
96 Strip Wells
price :
600 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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