catalog number :
MBS9320187
products type :
ELISA Kit
products full name :
Human Kinetochore protein Nuf2, NUF2 ELISA Kit
products short name :
[NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)]
products name syn :
[Human Kinetochore protein Nuf2 (NUF2) ELISA kit; CDCA1; CT106; NUF2R; NUF2; NDC80 kinetochore complex component; cancer/testis antigen 106; cell division cycle associated 1; NUF2; NDC80 kinetochore complex component; homolog (S. cerevisiae)]
other names :
[kinetochore protein Nuf2; Kinetochore protein Nuf2; kinetochore protein Nuf2; hNuf2; hNuf2R; hsNuf2; cancer/testis antigen 106; cell division cycle associated 1; cell division cycle-associated protein 1; NUF2, NDC80 kinetochore complex component, homolog; NUF2, NDC80 kinetochore complex component; Cell division cycle-associated protein 1]
products gene name :
[NUF2]
other gene names :
[NUF2; NUF2; CDCA1; CT106; NUF2R; CDCA1; NUF2R; hNuf2; hNuf2R; hsNuf2]
uniprot entry name :
NUF2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.312 ng/ml - 10 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NUF2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_113611.2
ncbi gb acc num :
NM_031423.3
ncbi mol weight :
54,304 Da
ncbi pathways :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); DNA Replication Pathway (105897); M Phase Pathway (105812); Mitotic M-M/G1 Phases Pathway (160943); Mitotic Prometaphase Pathway (105815)
ncbi summary :
This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
uniprot summary :
NUF2: Acts as a component of the essential kinetochore- associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Belongs to the NUF2 family. Protein type: DNA replication; Cancer Testis Antigen (CTA). Chromosomal Location of Human Ortholog: 1q23.3. Cellular Component: membrane; nucleus; cytosol; chromosome, pericentric region. Molecular Function: protein binding. Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation
size4 :
10x96-Strip-Wells