This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Keratin, type II cuticular Hb6, KRT86 ELISA Kit
catalog :
MBS9319554
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS9319554
products type :
ELISA Kit
products full name :
Human Keratin, type II cuticular Hb6, KRT86 ELISA Kit
products short name :
[keratin 86]
products name syn :
[Human Keratin; type II cuticular Hb6 (KRT86) ELISA kit; FLJ25176; HB6; Hb1; KRTHB1; KRTHB6; MNX; hHb6; hard keratin; type II; 6; keratin protein HB6; keratin; hair; basic; 6 (monilethrix) ; keratin 86]
other names :
[keratin, type II cuticular Hb6; Keratin, type II cuticular Hb6; keratin, type II cuticular Hb6; K86; keratin-86; hair keratin K2.11; keratin protein HB6; type-II keratin Kb26; hard keratin, type II, 6; type II hair keratin Hb6; keratin, hair, basic, 6 (monilethrix); keratin 86; Hair keratin K2.11; Keratin-86; K86; Type II hair keratin Hb6; Type-II keratin Kb26]
products gene name :
[KRT86]
other gene names :
[KRT86; KRT86; HB6; Hb1; MNX; hHb6; KRTHB1; KRTHB6; KRTHB6; K86]
uniprot entry name :
KRT86_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KRT86 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
14318422
ncbi acc num :
NP_002275.1
ncbi gb acc num :
NM_002284.3
uniprot acc num :
O43790
ncbi mol weight :
53,501 Da
ncbi summary :
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq, Jul 2008]
uniprot summary :
K86: Defects in KRT86 are a cause of monilethrix (MLTRX). Monilethrix is an autosomal dominant hair disorder characterized clinically by alopecia and follicular papules. Affected hairs have uniform elliptical nodes of normal thickness and intermittent constrictions, internodes at which the hair easily breaks. Usually only the scalp is involved, but in severe forms, the secondary sexual hair, eyebrows, eyelashes, and nails may also be affected. Belongs to the intermediate filament family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: extracellular space; keratin filament. Molecular Function: structural molecule activity. Disease: Monilethrix
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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