catalog number :
MBS9319517
products type :
ELISA Kit
products full name :
Human Mothers against decapentaplegic homolog 9, SMAD9 ELISA Kit
products short name :
[SMAD family member 9]
products name syn :
[Human Mothers against decapentaplegic homolog 9 (SMAD9) ELISA kit; MADH6; MADH9; SMAD8; SMAD8A; SMAD8B; MAD (mothers against decapentaplegic; Drosophila) homolog 9; MAD; mothers against decapentaplegic homolog 9; Mothers against decapentaplegic; drosophila; homolog o; SMAD family member 9]
other names :
[mothers against decapentaplegic homolog 9 isoform a; Mothers against decapentaplegic homolog 9; mothers against decapentaplegic homolog 9; MAD homolog 9; SMAD, mothers against DPP homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9; SMAD family member 9; Madh6; SMAD family member 9; SMAD 9; Smad9]
products gene name :
[SMAD9]
other gene names :
[SMAD9; SMAD9; PPH2; MADH6; MADH9; SMAD8; SMAD8A; SMAD8B; MADH6; MADH9; MAD homolog 9; Mothers against DPP homolog 9; SMAD 9; Smad9]
uniprot entry name :
SMAD9_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SMAD9 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001120689.1
ncbi gb acc num :
NM_001127217.2
ncbi mol weight :
52,493 Da
ncbi pathways :
ALK1 Signaling Events Pathway (137968); ALK2 Signaling Events Pathway (137983); BMP Receptor Signaling Pathway (137948); Signal Transduction Pathway (477114); Signaling By BMP Pathway (106336); TGF Beta Signaling Pathway (198810); TGF-beta Signaling Pathway (83064); TGF-beta Signaling Pathway (475)
ncbi summary :
The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
uniprot summary :
Smad8: transcription factor phosphorylated and activated by bone morphogenetic protein receptor kinases. Phosphorylated Smads dimerize with collaborating Smad4 and are translocated into the nucleus, where they regulate transcription of target genes. Participates in a wide range of critical processes including morphogenesis, cell-fate determination, proliferation, differentiation and apoptosis. Two alternatively spliced products have been described. Protein type: DNA-binding; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 13q12-q14. Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; intracellular; nucleus; cytosol. Molecular Function: protein binding; DNA binding; metal ion binding; transcription factor activity; transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity. Biological Process: BMP signaling pathway; Mullerian duct regression; transcription, DNA-dependent; ureteric bud development; transforming growth factor beta receptor signaling pathway; positive regulation of transcription, DNA-dependent; cartilage development; midbrain development; response to hypoxia; positive regulation of cell differentiation; protein amino acid phosphorylation; hindbrain development. Disease: Pulmonary Hypertension, Primary, 2
size4 :
10x96-Strip-Wells