Human ADAMTS-like protein 4, ADAMTSL4 ELISA Kit | MyBioSource MBS931950 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human ADAMTS-like protein 4, ADAMTSL4 ELISA Kit

catalog :

MBS931950

quantity :

24-Strip-Wells (LIMIT 1)

price :

240 USD

product information

catalog number :

MBS931950

products type :

ELISA Kit

products full name :

Human ADAMTS-like protein 4, ADAMTSL4 ELISA Kit

products short name :

[ADAMTS-like 4]

products name syn :

[Human ADAMTS-like protein 4 (ADAMTSL4) ELISA kit; TSRC1; OTTHUMP00000032789; thrombospondin repeat containing 1; ADAMTS-like 4]

other names :

[ADAMTS-like protein 4 isoform 3; ADAMTS-like protein 4; ADAMTS-like protein 4; thrombospondin repeat-containing protein 1; ADAMTS-like 4; Thrombospondin repeat-containing protein 1]

products gene name :

[ADAMTSL4]

other gene names :

[ADAMTSL4; ADAMTSL4; TSRC1; ECTOL2; ADAMTSL-4; TSRC1; PP1396; UNQ2803/PRO34012; ADAMTSL-4]

uniprot entry name :

ATL4_HUMAN

reactivity :

Human

sequence length :

1035

specificity :

This assay has high sensitivity and excellent specificity for detection of human ADAMTSL2. No significant cross-reactivity or interference between human ADAMTSL2 and analogues was observed.

storage stability :

Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

image1 heading :

Typical Testing Data/Standard Curve (for reference only)

other info1 :

Samples: Serum, Plasma, Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml-200 ng/ml. Sensitivity: 0.78 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.

products description :

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ADAMTSL2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ADAMTSL2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ADAMTSL2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ADAMTSL2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

ncbi gi num :

568384851

ncbi acc num :

NP_001275536.1

ncbi gb acc num :

NM_001288607.1

uniprot acc num :

Q6UY14

ncbi mol weight :

116,545 Da

ncbi pathways :

Metabolism Of Proteins Pathway (106230); O-glycosylation Of TSR Domain-containing Proteins Pathway (980460); O-linked Glycosylation Pathway (980459); Post-translational Protein Modification Pathway (161012)

ncbi summary :

This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014]

uniprot summary :

TSRC1: Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis. Defects in ADAMTSL4 are a cause of autosomal recessive isolated ectopia lentis (ARI-EL). ARI-EL is a rare condition characterized by partial or complete displacement of the lens from its space resulting from defective zonule formation. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 1q21.3. Cellular Component: endoplasmic reticulum lumen. Molecular Function: protein binding; protease binding; metalloendopeptidase activity. Biological Process: protein amino acid O-linked glycosylation; extracellular matrix organization and biogenesis; cellular protein metabolic process; positive regulation of apoptosis; apoptosis; proteolysis; post-translational protein modification. Disease: Ectopia Lentis 2, Isolated, Autosomal Recessive; Ectopia Lentis Et Pupillae

size1 :

24-Strip-Wells (LIMIT 1)

price1 :

240 USD

size2 :

48-Strip-Wells

price2 :

495

size3 :

96-Strip-Wells

price3 :

710

size4 :

5x96-Strip-Wells

price4 :

2705

size5 :

10x96-Strip-Wells

price5 :

5145