Human Histone-lysine N-methyltransferase EHMT2, EHMT2 ELISA Kit | MyBioSource MBS9319265 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Histone-lysine N-methyltransferase EHMT2, EHMT2 ELISA Kit

catalog :

MBS9319265

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9319265

products type :

ELISA Kit

products full name :

Human Histone-lysine N-methyltransferase EHMT2, EHMT2 ELISA Kit

products short name :

[euchromatic histone-lysine N-methyltransferase 2]

products name syn :

[Human Histone-lysine N-methyltransferase EHMT2 (EHMT2) ELISA kit; DAAP-66K18.3; BAT8; C6orf30; DKFZp686H08213; FLJ35547; G9A; KMT1C; NG36; G9A histone methyltransferase; H3-K9-HMTase 3; HLA-B associated transcript 8; ankyrin repeat-containing protein; histone H3-K9 me; euchromatic histone-lysine N-methyltransferase 2]

other names :

[histone-lysine N-methyltransferase EHMT2 isoform c; Histone-lysine N-methyltransferase EHMT2; histone-lysine N-methyltransferase EHMT2; H3-K9-HMTase 3; G9A histone methyltransferase; HLA-B associated transcript 8; lysine N-methyltransferase 1C; ankyrin repeat-containing protein; histone H3-K9 methyltransferase 3; histone-lysine N-methyltransferase, H3 lysine-9 specific 3; euchromatic histone-lysine N-methyltransferase 2; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9a]

products gene name :

[EHMT2]

other gene names :

[EHMT2; EHMT2; G9A; BAT8; GAT8; NG36; KMT1C; C6orf30; BAT8; C6orf30; G9A; KMT1C; NG36; H3-K9-HMTase 3]

uniprot entry name :

EHMT2_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EHMT2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

574957264

ncbi acc num :

NP_001276342.1

ncbi gb acc num :

NM_001289413.1

uniprot acc num :

Q96KQ7

ncbi mol weight :

132,370 Da

ncbi pathways :

Gene Expression Pathway (105937); Lysine Degradation Pathway (82956); Lysine Degradation Pathway (320); RNA Polymerase I Promoter Clearance Pathway (106551); RNA Polymerase I Transcription Pathway (106550); RNA Polymerase I Transcription Initiation Pathway (106553); RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway (160948); Regulation Of Androgen Receptor Activity Pathway (138027)

ncbi summary :

This gene is located in a gene cluster within the human major histocompatibility complex class III region on chromosome 6. This gene was thought to be two different genes, NG36 and G9a, adjacent to each other but recent publications show that there is only a single gene at this locus. The encoded protein is a histone methyltransferase, which may be involved in repression of transcription. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

uniprot summary :

EHMT2 iso4: Histone methyltransferase. Preferentially methylates Lys-9 of histone H3 and Lys-27 of histone H3 (in vitro). H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. Also methylates histone H1. Belongs to the histone-lysine methyltransferase family. Suvar3-9 subfamily. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts with GFI1B, WIZ and EHMT1. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Methyltransferase; Methyltransferase, protein lysine; EC 2.1.1.43; Amino Acid Metabolism - lysine degradation. Chromosomal Location of Human Ortholog: 6p21.31. Cellular Component: nucleoplasm; intermediate filament cytoskeleton; intracellular membrane-bound organelle; nuclear chromatin; nucleus. Molecular Function: protein binding; zinc ion binding; p53 binding; histone lysine N-methyltransferase activity (H3-K9 specific); protein-lysine N-methyltransferase activity; histone-lysine N-methyltransferase activity; histone lysine N-methyltransferase activity (H3-K27 specific). Biological Process: histone methylation; establishment and/or maintenance of chromatin architecture; peptidyl-lysine di-methylation; DNA methylation; negative regulation of transcription from RNA polymerase II promoter; regulation of DNA replication; histone H3-K9 methylation

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage