catalog number :
MBS9318935
products type :
ELISA Kit
products full name :
Human Ubiquitin-like-conjugating enzyme ATG10, ATG10 ELISA Kit
products short name :
[ATG10 autophagy related 10 homolog (S. cerevisiae)]
products name syn :
[Human Ubiquitin-like-conjugating enzyme ATG10 (ATG10) ELISA kit; APG10; APG10L; DKFZp586I0418; FLJ13954; pp12616; APG10 autophagy 10-like; ATG10 autophagy related 10 homolog (S. cerevisiae)]
other names :
[ubiquitin-like-conjugating enzyme ATG10; Ubiquitin-like-conjugating enzyme ATG10; ubiquitin-like-conjugating enzyme ATG10; autophagy-related protein 10; ATG10 autophagy related 10 homolog; autophagy related 10; Autophagy-related protein 10; APG10-like]
products gene name :
[ATG10]
other gene names :
[ATG10; ATG10; APG10; APG10L; pp12616; APG10L; PP12616; APG10-like]
uniprot entry name :
ATG10_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Canine Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 62.5pg/ml-2000pg/ml. Sensitivity: 10pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of ATF4 (hereafter termed "analyte") in undiluted original Canine serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001124500.1
ncbi gb acc num :
NM_001131028.1
ncbi mol weight :
25,279 Da
ncbi pathways :
Senescence And Autophagy Pathway (198780)
ncbi summary :
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]
uniprot summary :
ATG10: E2-like enzyme involved in autophagy. Acts as an E2-like enzyme that catalyzes the conjugation of ATG12 to ATG5. ATG12 conjugation to ATG5 is required for autophagy. Likely serves as an ATG5-recognition molecule. Not involved in ATG12 conjugation to ATG3. Belongs to the ATG10 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 6.3.2.-; Ubiquitin conjugating system; Autophagy. Chromosomal Location of Human Ortholog: 5q14.1. Cellular Component: cytoplasm; intracellular. Molecular Function: APG12 conjugating enzyme activity; ligase activity. Biological Process: protein transport; protein modification by small protein conjugation; positive regulation of protein modification process; protein amino acid lipidation; autophagy
size4 :
10x96-Strip-Wells