catalog number :
MBS9318876
products type :
ELISA Kit
products full name :
Human Zinc finger protein GLI2, GLI2 ELISA Kit
products short name :
[GLI family zinc finger 2]
products name syn :
[Human Zinc finger protein GLI2 (GLI2) ELISA kit; HPE9; THP1; THP2; GLI-Kruppel family member GLI2; OTTHUMP00000204359; glioma-associated oncogene family zinc finger 2; oncogene GLI2; tax helper protein 1; tax helper protein 2; tax-responsive element-2 h; GLI family zinc finger 2]
other names :
[zinc finger protein GLI2; Zinc finger protein GLI2; zinc finger protein GLI2; oncogene GLI2; tax helper protein 1; tax helper protein 2; GLI-Kruppel family member GLI2; tax-responsive element-2 holding protein; glioma-associated oncogene family zinc finger 2; tax-responsive element-25-bp sequence binding protein; GLI family zinc finger 2; Tax helper protein]
products gene name :
[GLI2]
other gene names :
[GLI2; GLI2; HPE9; PHS2; THP1; THP2; THP]
uniprot entry name :
GLI2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of GLI2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_005261.2
ncbi gb acc num :
NM_005270.4
ncbi mol weight :
167,783 Da
ncbi pathways :
Basal Cell Carcinoma Pathway (83113); Basal Cell Carcinoma Pathway (525); Hedgehog Signaling Pathway (198835); Hedgehog Signaling Events Mediated By Gli Proteins Pathway (137912); Hedgehog Signaling Pathway (83063); Hedgehog Signaling Pathway (474); Pathways In Cancer (83105); Signaling Events Mediated By The Hedgehog Family Pathway (137950)
ncbi summary :
This gene encodes a protein which belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]
uniprot summary :
Function: Acts as a transcriptional activator. May play a role during embryogenesis. Binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1. Is involved in the smoothened (SHH) signaling pathway.1 PublicationManual assertion based on experiment in:Ref.7
size4 :
10x96-Strip-Wells