product summary
Loading...
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Single Ig IL-1-related receptor, SIGIRR ELISA Kit
catalog :
MBS9318786
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9318786
products type :
ELISA Kit
products full name :
Human Single Ig IL-1-related receptor, SIGIRR ELISA Kit
products short name :
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
products name syn :
Human Single Ig IL-1-related receptor (SIGIRR) ELISA kit; MGC110992; TIR8; single Ig IL-1R-related molecule; single immunoglobulin domain IL1R1 related; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
other names :
single Ig IL-1-related receptor; Single Ig IL-1-related receptor; single Ig IL-1-related receptor; toll/interleukin-1 receptor 8; single Ig IL-1R-related molecule; single immunoglobulin domain IL1R1 related; single immunoglobulin domain-containing IL1R-related protein; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; Single Ig IL-1R-related molecule; Single immunoglobulin domain-containing IL1R-related protein; Toll/interleukin-1 receptor 8; TIR8
products gene name :
SIGIRR
other gene names :
SIGIRR; SIGIRR; TIR8; UNQ301/PRO342; TIR8
uniprot entry name :
SIGIR_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SIGIRR (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SIGIRR (hereafter termed this analyte) in Human serum, plasma and tissue homogenate samples.
ncbi gi num :
205277449
ncbi acc num :
NP_001128525.1
ncbi gb acc num :
NM_001135053.1
uniprot acc num :
Q6IA17
ncbi mol weight :
45,679 Da
ncbi pathways :
Activated TLR4 Signalling Pathway (106400); Immune System Pathway (106386); Innate Immune System Pathway (106387); MyD88:Mal Cascade Initiated On Plasma Membrane Pathway (106390); Toll Like Receptor 2 (TLR2) Cascade Pathway (106402); Toll Like Receptor 4 (TLR4) Cascade Pathway (106398); Toll Like Receptor TLR1:TLR2 Cascade Pathway (106403); Toll Like Receptor TLR6:TLR2 Cascade Pathway (106404); Toll Receptor Cascades Pathway (106388)
uniprot summary :
SIGIRR: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. Belongs to the interleukin-1 receptor family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral; Receptor, misc. Chromosomal Location of Human Ortholog: 11p15.5. Cellular Component: membrane; integral to membrane. Molecular Function: protein binding. Biological Process: negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of transcription factor activity; acute-phase response; negative regulation of cytokine and chemokine mediated signaling pathway; signal transduction; negative regulation of chemokine biosynthetic process
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!