Human Long/Medium-Wave-Sensitive Opsin 1 (OPN1LW/OPN1MW) ELISA Kit | MyBioSource MBS9318715 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Long/Medium-Wave-Sensitive Opsin 1 (OPN1LW/OPN1MW) ELISA Kit

catalog :

MBS9318715

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9318715

products type :

ELISA Kit

products full name :

Human Long/Medium-Wave-Sensitive Opsin 1 (OPN1LW/OPN1MW) ELISA Kit

products short name :

[Long/Medium-Wave-Sensitive Opsin 1 (OPN1LW/OPN1MW)]

products name syn :

[Human Long-wave-sensitive opsin 1 (OPN1LW) ELISA kit; hCG_41347; CBBM; CBP; RCP; red cone photoreceptor pigment; red-sensitive opsin; opsin 1 (cone pigments); long-wave-sensitive]

other names :

[Long-wave-sensitive opsin 1; Long-wave-sensitive opsin 1; long-wave-sensitive opsin 1; red-sensitive opsin; cone dystrophy 5 (X-linked); red cone photoreceptor pigment; opsin 1 (cone pigments), long-wave-sensitive; Red cone photoreceptor pigment; Red-sensitive opsin; ROP]

products gene name :

[OPN1LW]

other gene names :

[OPN1LW; OPN1LW; CBP; RCP; ROP; CBBM; COD5; RCP; ROP]

uniprot entry name :

OPSR_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Monkey Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of OPN1LW (hereafter termed "analyte") in undiluted original Monkey body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

129219

ncbi acc num :

P04000.1

uniprot acc num :

P04000

ncbi mol weight :

40,572 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); G Alpha (i) Signalling Events Pathway (119550); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); GPCRs, Class A Rhodopsin-like Pathway (198886); Opsins Pathway (106377); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)

ncbi summary :

This gene encodes for a light absorbing visual pigment of the opsin gene family. The encoded protein is called red cone photopigment or long-wavelength sensitive opsin. Opsins are G-protein coupled receptors with seven transmembrane domains, an N-terminal extracellular domain, and a C-terminal cytoplasmic domain. This gene and the medium-wavelength opsin gene are tandemly arrayed on the X chromosome and frequent unequal recombination and gene conversion may occur between these sequences. X chromosomes may have fusions of the medium- and long-wavelength opsin genes or may have more than one copy of these genes. Defects in this gene are the cause of partial, protanopic colorblindness. [provided by RefSeq, Jul 2008]

uniprot summary :

OPN1LW: Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. Defects in OPN1LW are the cause of partial colorblindness protan series (CBP); also known as protanopia. Defects in OPN1LW are a cause of blue cone monochromacy (BCM). A rare X-linked congenital stationary cone dysfunction syndrome characterized by the absence of functional long wavelength-sensitive and medium wavelength-sensitive cones in the retina. Color discrimination is severely impaired from birth, and vision is derived from the remaining preserved blue (S) cones and rod photoreceptors. BCM typically presents with reduced visual acuity, pendular nystagmus, and photophobia. Patients often have myopia. Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: Xq28. Cellular Component: integral to plasma membrane. Molecular Function: G-protein coupled receptor activity; photoreceptor activity. Biological Process: positive regulation of cytokinesis; G-protein coupled receptor protein signaling pathway; phototransduction, visible light; visual perception; signal transduction; retinoid metabolic process; protein-chromophore linkage. Disease: Blue Cone Monochromacy; Colorblindness, Partial, Protan Series

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage