catalog number :
MBS9318653
products type :
ELISA Kit
products full name :
Human Leucine carboxyl methyltransferase 1, LCMT1 ELISA Kit
products short name :
leucine carboxyl methyltransferase 1
products name syn :
Human Leucine carboxyl methyltransferase 1 (LCMT1) ELISA kit; CGI-68; LCMT; PPMT1; protein phosphatase methyltransferase 1; leucine carboxyl methyltransferase 1
other names :
leucine carboxyl methyltransferase 1 isoform b; Leucine carboxyl methyltransferase 1; leucine carboxyl methyltransferase 1; protein-leucine O-methyltransferase; protein phosphatase methyltransferase 1; [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1; leucine carboxyl methyltransferase 1; Protein-leucine O-methyltransferase; [Phosphatase 2A protein]-leucine-carboxy methyltransferase 1
products gene name :
LCMT1
other gene names :
LCMT1; LCMT1; LCMT; PPMT1; CGI-68; LCMT; CGI-68
uniprot entry name :
LCMT1_HUMAN
storage stability :
Store all reagents at 2-8 degree C
ncbi acc num :
NP_001027563.1
ncbi gb acc num :
NM_001032391.1
ncbi mol weight :
38,379 Da
ncbi summary :
LCMT1 catalyzes the methylation of the carboxyl group of the C-terminal leucine residue (leu309) of the catalytic subunit of protein phosphatase-2A (PPP2CA; MIM 176915) (De Baere et al., 1999 [PubMed 10600115]).[supplied by OMIM, Mar 2008]
uniprot summary :
LCMT1: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues. Belongs to the methyltransferase superfamily. LCMT family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Lipid Metabolism - androgen and estrogen; EC 2.1.1.233; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - histidine; Other Amino Acids Metabolism - selenoamino acid; Methyltransferase. Chromosomal Location of Human Ortholog: 16p12.1. Cellular Component: cytosol. Molecular Function: protein binding; C-terminal protein carboxyl methyltransferase activity; S-adenosylmethionine-dependent methyltransferase activity. Biological Process: regulation of apoptosis; protein amino acid methylation; C-terminal protein amino acid methylation; protein modification process; negative regulation of protein complex assembly