Human HERV-W_7q21.2 provirus ancestral Env polyprotein, ERVWE1 ELISA Kit | MyBioSource MBS9318236 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human HERV-W_7q21.2 provirus ancestral Env polyprotein, ERVWE1 ELISA Kit

catalog :

MBS9318236

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9318236

products type :

ELISA Kit

products full name :

Human HERV-W_7q21.2 provirus ancestral Env polyprotein, ERVWE1 ELISA Kit

products short name :

endogenous retroviral family W, env (C7) , member 1

products name syn :

Human HERV-W_7q21.2 provirus ancestral Env polyprotein (ERVWE1) ELISA kit; ENV; ENVW; HERV-7q; HERV-W-ENV; HERV7Q; HERVW; HERVWENV; HERV-7q envelope protein; HERV-W Env glycoprotein; HERV-W{7q21.1} provirus ancestral Env polyprotein; HERV-tryptophan envelope protein; envelope; endogenous retroviral family W; env (C7); member 1

other names :

HERV-W_7q21.2 provirus ancestral Env polyprotein; Syncytin-1; HERV-W_7q21.2 provirus ancestral Env polyprotein; env-W; enverin; syncytin A; syncytin-1; envelope protein; envelope glycoprotein; HERV-W Env glycoprotein; HERV-W envelope protein; HERV-7q envelope protein; envelope polyprotein gPr73; HERV-tryptophan envelope protein; endogenous retrovirus group W member 1; HERV-W{7q21.1} provirus ancestral Env polyprotein; endogenous retroviral family W, env(C7), member 1; human endogenous retrovirus W envC7-1 envelope protein; endogenous retrovirus group W, member 1; Endogenous retrovirus group W member 1; Env-W; Envelope polyprotein gPr73; Enverin; HERV-7q Envelope protein; HERV-W envelope protein; HERV-W_7q21.2 provirus ancestral Env polyprotein; SyncytinCleaved into the following 2 chains:Surface protein; SUAlternative name(s):gp50

products gene name :

ERVWE1

other gene names :

ERVW-1; ERVW-1; ENV; ENVW; HERVW; ERVWE1; HERV7Q; HERV-7q; HERVWENV; HERV-W-ENV; ERVWE1; SU; TM

uniprot entry name :

SYCY1_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich. Detection Range: 0.5ng/ml-16ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ERVWE1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

195963433

ncbi acc num :

NP_001124397.1

ncbi gb acc num :

NM_001130925.1

uniprot acc num :

Q9UQF0

ncbi mol weight :

59,866 Da

ncbi summary :

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Mar 2010]

uniprot summary :

ERVWE1: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis. Belongs to the gamma type-C retroviral envelope protein family. HERV class-I W env subfamily. Protein type: Cell surface; Membrane protein, integral. Chromosomal Location of Human Ortholog: 7q21.2. Cellular Component: plasma membrane; integral to membrane; viral envelope. Biological Process: anatomical structure morphogenesis; syncytium formation

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage