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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransferase 4 (ST3GAL4) ELISA Kit
catalog :
MBS9318191
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9318191
products type :
ELISA Kit
products full name :
Human CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransferase 4 (ST3GAL4) ELISA Kit
products short name :
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransferase 4 (ST3GAL4)
products name syn :
ST3 beta-galactoside alpha-2, 3-sialyltransferase 4; CGS23; FLJ11867; FLJ46764; NANTA3; SAT3; SIAT4; SIAT4C; ST3GalIV; STZ; alpha-3-N-acetylneuraminyltransferase sialyltransferase 4C (beta-galactosidase alpha-2; 3-sialytransferase) sialyltransferase 4C
other names :
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 2; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4; ST-4; SAT-3; SIAT4-C; ST3GalA.2; gal-NAc6S; alpha 2,3-ST 4; alpha 2,3-sialyltransferase IV; alpha-3-N-acetylneuraminyltransferase; beta-galactoside alpha-2,3-sialyltransferase 4; gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase; sialyltransferase 4C (beta-galactoside alpha-2,3-sialytransferase); sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase); ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Alpha 2,3-sialyltransferase IV; Gal-NAc6S; Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase; SAT-3; ST-4; ST3Gal IV; ST3GalIV; ST3GalA.2; STZ; Sialyltransferase 4C
products gene name :
ST3GAL4
other gene names :
ST3GAL4; ST3GAL4; STZ; SAT3; CGS23; SIAT4; NANTA3; SIAT4C; ST3GalIV; CGS23; NANTA3; SIAT4C; STZ; Alpha 2,3-ST 4; Beta-galactoside alpha-2,3-sialyltransferase 4; ST3GalIV; SIAT4-C
uniprot entry name :
SIA4C_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between Human ST3GAL4 and analogues was observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Serum, Plasma, Tissue Homogenate, Feces and Urine. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated ST3GAL4 concentrations in Human serum, plasma and other body fluids. Using Purified Human ST3GAL4 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add ST3GAL4 and ST3GAL4 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of ST3GAL4 in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated ST3GAL4 concentrations in Human serum, plasma and other body fluids. Using Purified Human ST3GAL4 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add ST3GAL4 and ST3GAL4 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of ST3GAL4 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
ncbi gi num :
363543346
ncbi acc num :
NP_001241686.1
ncbi gb acc num :
NM_001254757.1
uniprot acc num :
Q11206
ncbi mol weight :
38,045 Da
ncbi pathways :
Asparagine N-linked Glycosylation Pathway (161013); Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway (82995); Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway (370); Metabolism Of Proteins Pathway (106230); N-Glycan Antennae Elongation Pathway (187226); N-glycan Antennae Elongation In The Medial/trans-Golgi Pathway (187223); O-linked Glycosylation Of Mucins Pathway (530747); Post-translational Protein Modification Pathway (161012); Pre-NOTCH Expression And Processing Pathway (576265); Pre-NOTCH Processing In Golgi Pathway (576268)
ncbi summary :
This gene encodes a member of the glycosyltransferase 29 family, a group of enzymes involved in protein glycosylation. The encoded protein is targeted to Golgi membranes but may be proteolytically processed and secreted. The gene product may also be involved in the increased expression of sialyl Lewis X antigen seen in inflammatory responses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
uniprot summary :
ST3GAL4: It may catalyze the formation of the NeuAc-alpha-2,3- Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant. Also acts on the corresponding 1,3- galactosyl derivative. Belongs to the glycosyltransferase 29 family. 5 isoforms of the human protein are produced by alternative splicing. Protein type: Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Transferase; Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral; EC 2.4.99.-. Chromosomal Location of Human Ortholog: 11q24.2. Cellular Component: Golgi membrane; membrane; integral to Golgi membrane. Molecular Function: monosialoganglioside sialyltransferase activity; beta-galactoside alpha-2,3-sialyltransferase activity. Biological Process: keratan sulfate metabolic process; protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; glycosaminoglycan metabolic process; dolichol-linked oligosaccharide biosynthetic process; keratan sulfate biosynthetic process; carbohydrate metabolic process; pathogenesis; protein amino acid N-linked glycosylation via asparagine; cognition; post-translational protein modification
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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