Human Laminin subunit beta-3, LAMB3 ELISA Kit | MyBioSource MBS9318129 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Laminin subunit beta-3, LAMB3 ELISA Kit

catalog :

MBS9318129

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9318129

products type :

ELISA Kit

products full name :

Human Laminin subunit beta-3, LAMB3 ELISA Kit

products short name :

[laminin, beta 3]

products name syn :

[Human Laminin subunit beta-3 (LAMB3) ELISA kit; RP1-272L16.3; BM600-125KDA; FLJ99565; LAM5; LAMNB1; kalinin B1 chain; kalinin-140kDa; laminin B1k chain; laminin S B3 chain; laminin; beta 3 (nicein (125kD); kalinin (140kD); BM600 (125kD) ) ; nicein-125kD; laminin; beta 3]

other names :

[laminin subunit beta-3; Laminin subunit beta-3; laminin subunit beta-3; nicein-125kDa; kalinin-140kDa; kalinin B1 chain; laminin B1k chain; laminin S B3 chain; nicein subunit beta; kalinin subunit beta; epiligrin subunit bata; laminin-5 subunit beta; laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD)); laminin, beta 3; Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin-5 subunit beta; Nicein subunit beta]

products gene name :

[LAMB3]

other gene names :

[LAMB3; LAMB3; LAM5; LAMNB1; BM600-125KDA; LAMNB1]

uniprot entry name :

LAMB3_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 3.12 ug/ml - 100 ug/ml. Sensitivity: 1.0 ug/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of LAMB3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

62868215

ncbi acc num :

NP_000219.2

ncbi gb acc num :

NM_000228.2

uniprot acc num :

Q13751

ncbi mol weight :

129,572 Da

ncbi pathways :

Alpha6-Beta4 Integrin Signaling Pathway (198807); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); ECM-receptor Interaction Pathway (83068); ECM-receptor Interaction Pathway (479); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478)

ncbi summary :

The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

uniprot summary :

LAMB3: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Defects in LAMB3 are a cause of epidermolysis bullosa junctional Herlitz type (H-JEB); also known as junctional epidermolysis bullosa Herlitz-Pearson type. JEB defines a group of blistering skin diseases characterized by tissue separation which occurs within the dermo-epidermal basement membrane. H-JEB is a severe, infantile and lethal form. Death occurs usually within the first six months of life. Occasionally, children survive to teens. H-JEB is marked by bullous lesions at birth and extensive denudation of skin and mucous membranes that may be hemorrhagic. Defects in LAMB3 are a cause of generalized atrophic benign epidermolysis bullosa (GABEB). GABEB is a non- lethal, adult form of junctional epidermolysis bullosa characterized by life-long blistering of the skin, associated with hair and tooth abnormalities. Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted. Chromosomal Location of Human Ortholog: 1q32. Cellular Component: laminin-5 complex; extracellular region. Molecular Function: protein binding; protein complex binding; structural molecule activity. Biological Process: extracellular matrix disassembly; hemidesmosome assembly; extracellular matrix organization and biogenesis; epidermis development; brown fat cell differentiation; cell adhesion. Disease: Epidermolysis Bullosa, Junctional, Non-herlitz Type; Epidermolysis Bullosa, Junctional, Herlitz Type; Amelogenesis Imperfecta, Type Ia

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095