catalog number :
MBS9318071
products type :
ELISA Kit
products full name :
Human Serine/threonine-protein kinase PAK 6, PAK6 ELISA Kit
products short name :
[p21 protein (Cdc42/Rac) -activated kinase 6]
products name syn :
[Human Serine/threonine-protein kinase PAK 6 (PAK6) ELISA kit; PAK5; p21 (CDKN1A) -activated kinase 6; p21-activated kinase 6; p21-activated protein kinase 6; p21 protein (Cdc42/Rac) -activated kinase 6]
other names :
[serine/threonine-protein kinase PAK 6 isoform 1; Serine/threonine-protein kinase PAK 6; serine/threonine-protein kinase PAK 6; p21(CDKN1A)-activated kinase 6; p21 protein (Cdc42/Rac)-activated kinase 6; PAK-5; p21-activated kinase 6; PAK-6]
products gene name :
[PAK6]
other gene names :
[PAK6; PAK6; PAK5; PAK5; PAK-6]
uniprot entry name :
PAK6_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PAK6 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001122100.1
ncbi gb acc num :
NM_001128628.2
ncbi mol weight :
74,869 Da
ncbi pathways :
Activation Of Rac Pathway (119530); Androgen Receptor Signaling Pathway (198806); Axon Guidance Pathway (83065); Axon Guidance Pathway (476); Axon Guidance Pathway (105688); Developmental Biology Pathway (477129); ErbB Signaling Pathway (83049); ErbB Signaling Pathway (458); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067)
ncbi summary :
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
uniprot summary :
PAK6: a protein kinase of the STE20 family. Interacts with androgen receptor (AR), and cotranslocates into the nucleus with AR in response to androgen. Highly expressed in testis and prostate tissues. Protein type: Nuclear receptor co-regulator; Protein kinase, STE; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; STE group; STE20 family; PAKB subfamily. Chromosomal Location of Human Ortholog: 15q14. Cellular Component: cytoplasm; nucleus. Molecular Function: protein binding; ATP binding; receptor signaling protein serine/threonine kinase activity. Biological Process: regulation of transcription, DNA-dependent; apoptosis; cytoskeleton organization and biogenesis; mitotic cell cycle; protein amino acid phosphorylation
size4 :
10x96-Strip-Wells