catalog number :
MBS9318039
products type :
ELISA Kit
products full name :
Human Eukaryotic translation initiation factor 3 subunit D, EIF3D ELISA Kit
products short name :
[eukaryotic translation initiation factor 3, subunit D]
products name syn :
[Human Eukaryotic translation initiation factor 3 subunit D (EIF3D) ELISA kit; RP5-1119A7.12; EIF3S7; MGC126526; MGC17258; eIF3-p66; eIF3-zeta; OTTHUMP00000197901; eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3; subunit 7 zeta; 6; eukaryotic translation initiation factor 3; subunit D]
other names :
[eukaryotic translation initiation factor 3 subunit D; Eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3 subunit D; eIF3 p66; eIF-3-zeta; translation initiation factor eIF3 p66 subunit; eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; eukaryotic translation initiation factor 3, subunit D; Eukaryotic translation initiation factor 3 subunit 7; eIF-3-zeta; eIF3 p66]
products gene name :
[EIF3D]
other gene names :
[EIF3D; EIF3D; EIF3S7; eIF3-p66; eIF3-zeta; EIF3S7; eIF3d]
uniprot entry name :
EIF3D_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich (Quantitative). Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of EIF3D (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_003744.1
ncbi gb acc num :
NM_003753.3
ncbi mol weight :
63,973 Da
ncbi pathways :
Activation Of The MRNA Upon Binding Of The Cap-binding Complex And EIFs, And Subsequent Binding To 43S Pathway (105970); Cap-dependent Translation Initiation Pathway (105967); Eukaryotic Translation Initiation Pathway (105966); Formation Of A Pool Of Free 40S Subunits Pathway (105968); Formation Of The Ternary Complex, And Subsequently, The 43S Complex Pathway (105969); GTP Hydrolysis And Joining Of The 60S Ribosomal Subunit Pathway (105973); Gene Expression Pathway (105937); L13a-mediated Translational Silencing Of Ceruloplasmin Expression Pathway (160955); Metabolism Of Proteins Pathway (106230); RNA Transport Pathway (177876)
ncbi summary :
Eukaryotic translation initiation factor-3 (eIF3), the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain the 40S and 60S ribosomal subunits in a dissociated state. It is also thought to play a role in the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and by promoting mRNA binding. The protein encoded by this gene is the major RNA binding subunit of the eIF3 complex. [provided by RefSeq, Jul 2008]
uniprot summary :
eIF3-zeta: eukaryotic translation initiation factor 3 subunit 7. Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. Associates with the subunit p170 of eIF-3. eIF-3 is composed of at least 12 different subunits. Protein type: Translation; RNA-binding; Translation initiation. Chromosomal Location of Human Ortholog: 22q13.1. Cellular Component: eukaryotic translation initiation factor 3 complex; membrane; cytosol. Molecular Function: protein binding; translation initiation factor activity. Biological Process: cellular protein metabolic process; translation; translational initiation; formation of translation initiation complex; gene expression; formation of translation preinitiation complex; regulation of translational initiation
size4 :
10x96-Strip-Wells