ELISA/assay

Human Stabilin-1, STAB1 ELISA Kit

MBS9317713

48-Strip-Wells

435 USD

ELISA Kit

Human Stabilin-1, STAB1 ELISA Kit

stabilin 1

Human Stabilin-1 (STAB1) ELISA kit; CLEVER-1; FEEL-1; FELE-1; FEX1; KIAA0246; STAB-1; MS-1 antigen; common lymphatic endothelial and vascular endothelial receptor-1; fasciclin egf-like; laminin-type egf-like; and link domain-containing; stabilin 1

stabilin-1; Stabilin-1; stabilin-1; MS-1 antigen; common lymphatic endothelial and vascular endothelial receptor-1; fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-1; fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1; stabilin 1; Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1; FEEL-1; MS-1 antigen

STAB1

STAB1; STAB1; FEX1; FEEL-1; FELE-1; STAB-1; CLEVER-1; FEEL1; KIAA0246; FEEL-1

STAB1_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of STAB1 (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

61743978

NP_055951.2

NM_015136.2

Q9NY15

275,482 Da

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 16 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to endocytose ligands such as low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein rapidly cycles between the plasma membrane and early endosomes. [provided by RefSeq, Jul 2008]

STAB1: Acts as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. When inhibited in endothelial tube formation assays, there is a marked decrease in cell-cell interactions, suggesting a role in angiogenesis. Involved in the delivery of newly synthesized CHID1/SI-CLP from the biosynthetic compartment to the endosomal/lysosomal system. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Receptor, misc.; Membrane protein, integral. Chromosomal Location of Human Ortholog: 3p21.1. Cellular Component: integral to plasma membrane; plasma membrane. Molecular Function: low-density lipoprotein receptor activity; protein binding; hyaluronic acid binding; low-density lipoprotein binding; protein disulfide oxidoreductase activity; scavenger receptor activity. Biological Process: receptor-mediated endocytosis; negative regulation of angiogenesis; cell-cell signaling; defense response to bacterium; cell adhesion; inflammatory response

48-Strip-Wells

435 USD

96-Strip-Wells

600