product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human B-cell lymphoma/leukemia 11A, BCL11A ELISA Kit
catalog :
MBS9317701
quantity :
48-Strip-Wells
price :
435 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9317701
products type :
ELISA Kit
products full name :
Human B-cell lymphoma/leukemia 11A, BCL11A ELISA Kit
products short name :
B-cell CLL/lymphoma 11A (zinc finger protein)
products name syn :
Human B-cell lymphoma/leukemia 11A (BCL11A) ELISA kit; BCL11A-L; BCL11A-S; BCL11A-XL; CTIP1; EVI9; FLJ10173; FLJ34997; HBFQTL5; KIAA1809; ZNF856; B-cell CLL/lymphoma 11A; C2H2-type zinc finger protein; ecotropic viral integration site 9 homolog; B-cell CLL/lymphoma 11A (zinc finger protein)
other names :
B-cell lymphoma/leukemia 11A isoform 2; B-cell lymphoma/leukemia 11A; B-cell lymphoma/leukemia 11A; EVI-9; BCL-11A; zinc finger protein 856; C2H2-type zinc finger protein; COUP-TF-interacting protein 1; ecotropic viral integration site 9 homolog; ecotropic viral integration site 9 protein homolog; B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A; COUP-TF-interacting protein 1; Ecotropic viral integration site 9 protein homolog; EVI-9; Zinc finger protein 856
products gene name :
BCL11A
other gene names :
BCL11A; BCL11A; EVI9; CTIP1; ZNF856; HBFQTL5; BCL11A-L; BCL11A-S; BCL11a-M; BCL11A-XL; CTIP1; EVI9; KIAA1809; ZNF856; BCL-11A; EVI-9
uniprot entry name :
BC11A_HUMAN
reactivity :
Human
storage stability :
Store all reagents at 2-8 degree C
ncbi gi num :
20336307
ncbi acc num :
NP_060484.2
ncbi gb acc num :
NM_018014.3
uniprot acc num :
Q9H165
ncbi mol weight :
91,197 Da
ncbi summary :
This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
Bcl-11A: Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1. Chromosomal aberrations involving BCL11A may be a cause of lymphoid malignancies. Translocation t(2;14)(p13;q32.3) causes BCL11A deregulation and amplification. 6 isoforms of the human protein are produced by alternative splicing. Protein type: C2H2-type zinc finger protein; Nuclear receptor co-regulator; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 2p16.1. Cellular Component: nucleoplasm; cytoplasm; nucleus. Molecular Function: protein homodimerization activity; protein heterodimerization activity; metal ion binding; transcription corepressor activity. Biological Process: protein sumoylation; transcription, DNA-dependent; B cell differentiation; regulation of dendrite development; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; negative regulation of collateral sprouting; negative regulation of axon extension; positive regulation of collateral sprouting; T cell differentiation; negative regulation of protein homooligomerization
size1 :
48-Strip-Wells
price1 :
435 USD
size2 :
96-Strip-Wells
price2 :
600
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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