catalog number :
MBS9317633
products type :
ELISA Kit
products full name :
Human Synaptotagmin-2, SYT2 ELISA Kit
products short name :
[synaptotagmin II]
products name syn :
[Human Synaptotagmin-2 (SYT2) ELISA kit; FLJ42519; SytII; synaptotagmin 2; synaptotagmin II]
other names :
[synaptotagmin-2; Synaptotagmin-2; synaptotagmin-2; synaptotagmin 2; synaptotagmin II; Synaptotagmin II; SytII]
products gene name :
[SYT2]
other gene names :
[SYT2; SYT2; SytII; SytII]
uniprot entry name :
SYT2_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 6.25 ng/ml - 200 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SYT2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001129976.1
ncbi gb acc num :
NM_001136504.1
ncbi mol weight :
46,872 Da
ncbi pathways :
Botulinum Neurotoxicity Pathway (105734); Disease Pathway (530764); Neuronal System Pathway (106513); Translocation Of BoNT Light Chain Pathway (105735)
ncbi summary :
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).[supplied by OMIM, Mar 2008]
uniprot summary :
SYT2: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. Belongs to the synaptotagmin family. Protein type: Vesicle; Calcium-binding; Membrane protein, integral; Lipid-binding. Chromosomal Location of Human Ortholog: 1q32.1. Cellular Component: intracellular membrane-bound organelle; synaptic vesicle membrane; plasma membrane; integral to membrane; cell junction. Molecular Function: protein binding; calcium-dependent phospholipid binding; transporter activity; calcium ion binding. Biological Process: transport; pathogenesis. Disease: Myasthenic Syndrome, Presynaptic, Congenital, With Or Without Motor Neuropathy
size4 :
10x96-Strip-Wells