catalog number :
MBS9317100
products type :
ELISA Kit
products full name :
Human Vacuole membrane protein 1, TMEM49 ELISA Kit
products short name :
[transmembrane protein 49]
products name syn :
[Human Vacuole membrane protein 1 (TMEM49) ELISA kit; DKFZp566I133; VMP1; ; transmembrane protein 49]
other names :
[vacuole membrane protein 1; Vacuole membrane protein 1; vacuole membrane protein 1; transmembrane protein 49; transport and golgi organization 5 homolog; ectopic P-granules autophagy protein 3 homolog; vacuole membrane protein 1; Transmembrane protein 49]
products gene name :
[TMEM49]
other gene names :
[VMP1; VMP1; EPG3; TANGO5; TMEM49; TDC1; TMEM49; HSPC292]
uniprot entry name :
VMP1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/mL. Sensitivity: 5.0 pg/mL
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TMEM49 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_112200.2
ncbi gb acc num :
NM_030938.3
ncbi mol weight :
46,238 Da
uniprot summary :
VMP1: Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. Plays a role in the initial stages of the autophagic process through its interaction with BECN1. Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions. Interacts with BECN1. Interacts with TJP1. Interacts with TP53INP2. Belongs to the VMP1 family. Protein type: Membrane protein, integral; Endoplasmic reticulum; Membrane protein, multi-pass. Chromosomal Location of Human Ortholog: 17q23.1. Cellular Component: ER-Golgi intermediate compartment membrane; membrane; endoplasmic reticulum; integral to membrane; plasma membrane. Molecular Function: protein binding. Biological Process: endoplasmic reticulum organization and biogenesis; cell-cell adhesion; exocytosis; autophagy; regulation of autophagy; Golgi organization and biogenesis; embryo implantation
size4 :
10x96-Strip-Wells