catalog number :
MBS9317089
products type :
ELISA Kit
products full name :
Mouse Monocarboxylate transporter 1, SLC16A1 ELISA Kit
products short name :
[solute carrier family 16, member 1 (monocarboxylic acid transporter 1)]
products name syn :
[Mouse Monocarboxylate transporter 1 (SLC16A1) ELISA kit; FLJ36745; HHF7; MCT; MCT1; MGC44475; monocarboxylate transporter 1; solute carrier family 16 (monocarboxylic acid transporters); member 1; solute carrier family 16; member 1; solute carrier family 16; member 1 (monocarboxylic acid transporter 1)]
other names :
[monocarboxylate transporter 1; Monocarboxylate transporter 1; monocarboxylate transporter 1; solute carrier family 16 member 1; solute carrier family 16 (monocarboxylic acid transporters), member 1; Solute carrier family 16 member 1]
products gene name :
[SLC16A1]
other gene names :
[Slc16a1; Slc16a1; Mct1; AL022710; Mct1; MCT 1]
uniprot entry name :
MOT1_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Assay Type: Sandwich (Quantitative). Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SLC16A1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_033222.1
ncbi gb acc num :
NM_009196.4
ncbi mol weight :
53,267 Da
ncbi pathways :
Basigin Interactions Pathway (575509); Cell Surface Interactions At The Vascular Wall Pathway (575507); Hemostasis Pathway (575479); Metabolism Pathway (574739); Proton-coupled Monocarboxylate Transport Pathway (575035); Pyruvate Metabolism Pathway (574831); Pyruvate Metabolism And Citric Acid (TCA) Cycle Pathway (574830); SLC-mediated Transmembrane Transport Pathway (575016); The Citric Acid (TCA) Cycle And Respiratory Electron Transport Pathway (574829); Transmembrane Transport Of Small Molecules Pathway (575012)
uniprot summary :
MCT1: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Defects in SLC16A1 are the cause of symptomatic deficiency in lactate transport (SDLT); also known as erythrocyte lactate transporter defect. Deficiency of lactate transporter may result in an acidic intracellular environment created by muscle activity with consequent degeneration of muscle and release of myoglobin and creatine kinase. This defect might compromise extreme performance in otherwise healthy individuals. Defects in SLC16A1 are the cause of familial hyperinsulinemic hypoglycemia type 7 (HHF7); also known as exercise-induced hyperinsulinemic hypoglycemia. HHF7 is a dominantly inherited hypoglycemic disorder characterized by inappropriate insulin secretion during anaerobic exercise or on pyruvate load. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. Protein type: Transporter, SLC family; Mitochondrial; Membrane protein, multi-pass; Membrane protein, integral; Transporter. Cellular Component: centrosome; membrane; mitochondrion; integral to plasma membrane; integral to membrane; plasma membrane. Molecular Function: protein homodimerization activity; symporter activity; lactate transmembrane transporter activity; secondary active monocarboxylate transmembrane transporter activity. Biological Process: response to food; transport; centrosome organization and biogenesis; lipid metabolic process; glucose homeostasis; transmembrane transport; regulation of insulin secretion; behavioral response to nutrient; organic anion transport
size4 :
10x96-Strip-Wells