Human Wiskott-Aldrich syndrome protein family member 3, WASF3 ELISA Kit | MyBioSource MBS9316818 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Wiskott-Aldrich syndrome protein family member 3, WASF3 ELISA Kit

catalog :

MBS9316818

quantity :

48-Strip-Wells

price :

435 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9316818

products type :

ELISA Kit

products full name :

Human Wiskott-Aldrich syndrome protein family member 3, WASF3 ELISA Kit

products short name :

WAS protein family, member 3

products name syn :

Human Wiskott-Aldrich syndrome protein family member 3 (WASF3) ELISA kit; RP11-496O3.2; Brush-1; KIAA0900; SCAR3; WAVE3; WASP family Verprolin-homologous protein 3; WAS protein family; member 3

other names :

wiskott-Aldrich syndrome protein family member 3 isoform 1; Wiskott-Aldrich syndrome protein family member 3; wiskott-Aldrich syndrome protein family member 3; protein WAVE-3; WASP family Verprolin-homologous protein 3; verprolin homology domain-containing protein 3; WAS protein family, member 3; Protein WAVE-3; Verprolin homology domain-containing protein 3

products gene name :

WASF3

other gene names :

WASF3; WASF3; SCAR3; WAVE3; Brush-1; KIAA0900; SCAR3; WAVE3; WASP family protein member 3

uniprot entry name :

WASF3_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between Human WASF3 and analogues was observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Serum, Plasma, Tissue Homogenate, Feces and Urine. Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.

other info2 :

Intended Uses: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated WASF3 concentrations in Human serum, plasma and other body fluids. Using Purified Human WASF3 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add WASF3 and WASF3 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of WASF3 in the samples is then determined by comparing the O.D. of the samples to the standard curve. Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]

products description :

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! It is intended to be determinated WASF3 concentrations in Human serum, plasma and other body fluids. Using Purified Human WASF3 antibody to coat Microelisa Stripplate wells to make solid-phase antibody, then add WASF3 and WASF3 antibody which has been labeled with HRP to wells, then the reactants become antibody-antigen-antibody-enzyme complex, after washing completely, add TMB substrate solution, TMB substrate becomes blue color under HRP enzyme-catalyzed, reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. The concentration of WASF3 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

ncbi gi num :

13699803

ncbi acc num :

NP_006637.2

ncbi gb acc num :

NM_006646.5

uniprot acc num :

Q9UPY6

ncbi mol weight :

55,293 Da

ncbi pathways :

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Fc Gamma R-mediated Phagocytosis Pathway (114228); Fc Gamma R-mediated Phagocytosis Pathway (106590)

ncbi summary :

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014]

uniprot summary :

WASF3: Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape. Binds actin and the Arp2/3 complex. Expressed in ovary and brain. Belongs to the SCAR/WAVE family. Protein type: Actin-binding; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 13q12. Cellular Component: cytoskeleton; lamellipodium; cytoplasm. Molecular Function: actin binding. Biological Process: positive regulation of myelination; lamellipodium biogenesis; regulation of cell shape; actin filament polymerization; cytoskeleton organization and biogenesis; protein complex assembly; oligodendrocyte development

size1 :

48-Strip-Wells

price1 :

435 USD

size2 :

96-Strip-Wells

price2 :

600

more info or order :

MyBioSource product webpage