Human Killer cell immunoglobulin-like receptor 2DL4, KIR2DL4 ELISA Kit | MyBioSource MBS9316732 product information

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product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Killer cell immunoglobulin-like receptor 2DL4, KIR2DL4 ELISA Kit

catalog :

MBS9316732

quantity :

48-Strip-Wells

price :

470 USD

product information

catalog number :

MBS9316732

products type :

ELISA Kit

products full name :

Human Killer cell immunoglobulin-like receptor 2DL4, KIR2DL4 ELISA Kit

products short name :

[killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4]

products name syn :

[Human Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4) ELISA kit; CD158D; G9P; KIR103; KIR103AS; NK cell receptor; natural killer cell inhibitory receptor; killer cell immunoglobulin-like receptor; two domains; long cytoplasmic tail; 4]

other names :

[killer cell immunoglobulin-like receptor 2DL4 isoform c; Killer cell immunoglobulin-like receptor 2DL4; killer cell immunoglobulin-like receptor 2DL4; NK cell receptor; killer Ig receptor; CD158 antigen-like family member D; MHC class I NK cell receptor KIR103AS; killer cell inhibitory receptor 103AS; natural killer cell inhibitory receptor; killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4; CD158 antigen-like family member D; G9P; Killer cell inhibitory receptor 103AS; KIR-103AS; MHC class I NK cell receptor KIR103AS; CD_antigen: CD158d]

products gene name :

[KIR2DL4]

other gene names :

[KIR2DL4; KIR2DL4; G9P; CD158D; KIR103; KIR103AS; KIR-103AS; CD158D; KIR103AS; KIR-103AS]

uniprot entry name :

KI2L4_HUMAN

reactivity :

Human

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 6.25ng/ml-200ng/ml. Sensitivity: 1.0ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of KIR2DL4 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

124107610

ncbi acc num :

NP_001074239.1

ncbi gb acc num :

NM_001080770.1

uniprot acc num :

Q99706

ncbi mol weight :

41,487 Da

ncbi pathways :

Adaptive Immune System Pathway (366160); Antigen Processing And Presentation Pathway (83074); Antigen Processing And Presentation Pathway (485); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413); Natural Killer Cell Mediated Cytotoxicity Pathway (83079); Natural Killer Cell Mediated Cytotoxicity Pathway (490)

ncbi summary :

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the "framework" loci that is present on all haplotypes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

uniprot summary :

KIR2DL4: Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis. Belongs to the immunoglobulin superfamily. 6 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 19q13.4. Cellular Component: membrane; integral to plasma membrane; plasma membrane. Molecular Function: protein binding; transmembrane receptor activity. Biological Process: regulation of immune response; cellular defense response; signal transduction

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095