Mouse Peroxisomal acyl-coenzyme A oxidase 1, ACOX1 ELISA Kit | MyBioSource MBS9316691 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Peroxisomal acyl-coenzyme A oxidase 1, ACOX1 ELISA Kit

catalog :

MBS9316691

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9316691

products type :

ELISA Kit

products full name :

Mouse Peroxisomal acyl-coenzyme A oxidase 1, ACOX1 ELISA Kit

products short name :

[acyl-Coenzyme A oxidase 1, palmitoyl]

products name syn :

[Mouse Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) ELISA kit; ACOX; MGC1198; PALMCOX; SCOX; acyl-CoA oxidase; straight-chain; acyl-Coenzyme A oxidase 1; peroxisomal fatty acyl-CoA oxidase; acyl-Coenzyme A oxidase 1; palmitoyl]

other names :

[peroxisomal acyl-coenzyme A oxidase 1 isoform 2; Peroxisomal acyl-coenzyme A oxidase 1; peroxisomal acyl-coenzyme A oxidase 1; palmitoyl-CoA oxidase; peroxisomal fatty acyl-coenzyme A oxidase; peroxisomal straight-chain Acyl-CoA oxidase; acyl-Coenzyme A oxidase 1, palmitoyl; Palmitoyl-CoA oxidase]

products gene name :

[ACOX1]

other gene names :

[Acox1; Acox1; AOX; Acox; Paox; D130055E20Rik; Acox; Paox; AOX]

uniprot entry name :

ACOX1_MOUSE

reactivity :

Mouse

specificity :

No significant cross-reactivity or interference between this analyte and analogues is observed.

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Fish Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of ACOX1 (hereafter termed "analyte") in undiluted original Fish serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

429484484

ncbi acc num :

NP_001258827.1

ncbi gb acc num :

NM_001271898.1

uniprot acc num :

Q9R0H0

ncbi mol weight :

74,649 Da

ncbi pathways :

Arachidonic Acid Metabolism Via COX (Cyclooxygenase) Pathway (522976); Arachidonic Acid Metabolism Via LOX (Lipooxygenase) Pathway (522978); Beta-oxidation Of Very Long Chain Fatty Acids Pathway (574786); Biosynthesis Of Unsaturated Fatty Acids Pathway (83231); Biosynthesis Of Unsaturated Fatty Acids Pathway (429); Fatty Acid Metabolism Pathway (83135); Fatty Acid Metabolism Pathway (296); Metabolism Pathway (574739); Metabolism Of Lipids And Lipoproteins Pathway (574754); Omega-3 And Omega-6 Unsaturated Fatty Acids Biosynthesis Pathway (522979)

ncbi summary :

This gene encodes a member of the acyl-coenzyme A oxidase family. The encoded protein is localized to peroxisomes and is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-coenzyme A to 2-trans-enoyl-coenzyme A. Disruption of this gene results in microvesicular steatohepatitis, spontaneous peroxisome proliferation, and the eventual development of hepatocellular carcinomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]

uniprot summary :

ACOX1: Catalyzes the desaturation of acyl-CoAs to 2-trans- enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy- palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl- CoA. Defects in ACOX1 are the cause of adrenoleukodystrophy pseudoneonatal (Pseudo-NALD); also known as peroxisomal acyl-CoA oxidase deficiency. Pseudo-NALD is a peroxisomal single-enzyme disorder. Clinical features include mental retardation, leukodystrophy, seizures, mild hepatomegaly, hearing deficit. Pseudo-NALD is characterized by increased plasma levels of very-long chain fatty cids, due to decreased or absent peroxisome acyl-CoA oxidase activity. Peroxisomes are intact and functioning. Belongs to the acyl-CoA oxidase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.3.3.6; Oxidoreductase; Lipid Metabolism - fatty acid; Lipid Metabolism - unsaturated fatty acid biosynthesis; Lipid Metabolism - alpha-linolenic acid. Cellular Component: nucleoplasm; peroxisomal membrane; membrane; intracellular membrane-bound organelle; mitochondrion; cytoplasm; plasma membrane; nucleolus; peroxisome; nucleus. Molecular Function: palmitoyl-CoA oxidase activity; acyl-CoA dehydrogenase activity; acyl-CoA oxidase activity; FAD binding; oxidoreductase activity, acting on the CH-CH group of donors; protein N-terminus binding; oxidoreductase activity; fatty acid binding; PDZ domain binding; receptor binding. Biological Process: peroxisome fission; fatty acid beta-oxidation using acyl-CoA oxidase; generation of precursor metabolites and energy; fatty acid beta-oxidation; very-long-chain fatty acid metabolic process; metabolic process; lipid homeostasis; spermatogenesis; fatty acid oxidation; lipid metabolic process; fatty acid metabolic process; prostaglandin metabolic process

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage