ELISA/assay

Human Folate transporter 1, SLC19A1 ELISA Kit

MBS9316350

48-Strip-Wells

470 USD

ELISA Kit

Human Folate transporter 1, SLC19A1 ELISA Kit

[solute carrier family 19 (folate transporter) , member 1]

[Human Folate transporter 1 (SLC19A1) ELISA kit; CHMD; FOLT; IFC1; REFC; RFC1; reduced folate carrier; solute carrier family 19 member 1; solute carrier family 19 (folate transporter); member 1]

[folate transporter 1 isoform 2; Folate transporter 1; folate transporter 1; RFC; IFC-1; intestinal folate carrier 1; placental folate transporter; reduced folate carrier protein; solute carrier family 19 member 1; solute carrier family 19 (folate transporter), member 1; Intestinal folate carrier 1; IFC-1; Placental folate transporter; Reduced folate carrier protein; RFC; Solute carrier family 19 member 1]

[SLC19A1]

[SLC19A1; SLC19A1; CHMD; FOLT; IFC1; REFC; RFC1; FLOT1; RFC1; FOLT; IFC-1; RFC]

S19A1_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of SLC19A1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

327199314

NP_001192135.1

NM_001205206.1

P41440

64,868 Da

Defective AMN Causes Hereditary Megaloblastic Anemia 1 Pathway (906000); Defective BTD Causes Biotidinase Deficiency Pathway (906015); Defective CD320 Causes Methylmalonic Aciduria Pathway (906012); Defective CUBN Causes Hereditary Megaloblastic Anemia 1 Pathway (906001); Defective GIF Causes Intrinsic Factor Deficiency Pathway (906004); Defective HLCS Causes Multiple Carboxylase Deficiency Pathway (906014); Defective LMBRD1 Causes Methylmalonic Aciduria And Homocystinuria Type CblF Pathway (906003); Defective MMAA Causes Methylmalonic Aciduria Type CblA Pathway (906010); Defective MMAB Causes Methylmalonic Aciduria Type CblB Pathway (906009); Defective MMACHC Causes Methylmalonic Aciduria And Homocystinuria Type CblC Pathway (906005)

The membrane protein encoded by this gene is a transporter of folate and is involved in the regulation of intracellular concentrations of folate. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

SLC19A1: a transporter protein. Transports reduced folate, antitumor agents and folate antagonists such as methotrexate. Apparently involved in methotrexate resistance in various cancers and neural tube defects. Protein type: Membrane protein, multi-pass; Transporter, SLC family; Transporter; Membrane protein, integral. Chromosomal Location of Human Ortholog: 21q22.3. Cellular Component: membrane; integral to plasma membrane; plasma membrane. Molecular Function: folic acid transporter activity; methotrexate transporter activity; folic acid binding. Biological Process: vitamin metabolic process; methotrexate transport; folic acid metabolic process; water-soluble vitamin metabolic process; folic acid transport

48-Strip-Wells

470 USD

96-Strip-Wells

680

5x96-Strip-Wells

3100

10x96-Strip-Wells

6095