catalog number :
MBS9316212
products type :
ELISA Kit
products full name :
Human Adipocyte enhancer-binding protein 1, AEBP1 ELISA Kit
products short name :
[AE binding protein 1]
products name syn :
[Human Adipocyte enhancer-binding protein 1 (AEBP1) ELISA kit; ACLP; FLJ33612; AE-binding protein 1; adipocyte enhancer binding protein 1; aortic carboxypeptidase-like protein; AE binding protein 1]
other names :
[adipocyte enhancer-binding protein 1; Adipocyte enhancer-binding protein 1; adipocyte enhancer-binding protein 1; aortic carboxypeptidase-like protein; AE binding protein 1; Aortic carboxypeptidase-like protein]
products gene name :
[AEBP1]
other gene names :
[AEBP1; AEBP1; ACLP; ACLP; AE-binding protein 1]
uniprot entry name :
AEBP1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of AEBP1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001120.3
ncbi gb acc num :
NM_001129.4
ncbi mol weight :
130,929 Da
ncbi summary :
This gene encodes a member of carboxypeptidase A protein family. The encoded protein may function as a transcriptional repressor and play a role in adipogenesis and smooth muscle cell differentiation. Studies in mice suggest that this gene functions in wound healing and abdominal wall development. Overexpression of this gene is associated with glioblastoma. [provided by RefSeq, May 2013]
uniprot summary :
AEBP1: May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I- kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor. Belongs to the peptidase M14 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted, signal peptide; Secreted; Transcription factor. Chromosomal Location of Human Ortholog: 7p13. Cellular Component: extracellular matrix; extracellular space; cytoplasm; nucleus. Molecular Function: calmodulin binding; zinc ion binding; carboxypeptidase activity; transcription corepressor activity; metallocarboxypeptidase activity; transcription factor activity. Biological Process: muscle development; transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; proteolysis; skeletal development
size4 :
10x96-Strip-Wells