product summary
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company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Myotubularin-related protein 2, MTMR2 ELISA Kit
catalog :
MBS9316181
quantity :
48-Strip-Wells
price :
470 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS9316181
products type :
ELISA Kit
products full name :
Human Myotubularin-related protein 2, MTMR2 ELISA Kit
products short name :
[myotubularin related protein 2]
products name syn :
[Human Myotubularin-related protein 2 (MTMR2) ELISA kit; CMT4B; CMT4B1; KIAA1073; OTTHUMP00000204447; myotubularin-related protein 2; myotubularin related protein 2]
other names :
[myotubularin-related protein 2 isoform 2; Myotubularin-related protein 2; myotubularin-related protein 2; myotubularin related protein 2]
products gene name :
[MTMR2]
other gene names :
[MTMR2; MTMR2; CMT4B; CMT4B1; KIAA1073]
uniprot entry name :
MTMR2_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 0.5 ng/ml - 16 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MTMR2 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
343790884
ncbi acc num :
NP_001230500.1
ncbi gb acc num :
NM_001243571.1
uniprot acc num :
Q13614
ncbi mol weight :
73,381 Da
ncbi pathways :
Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PI Metabolism Pathway (645332); Phospholipid Metabolism Pathway (645312); Synthesis Of PIPs At The Early Endosome Membrane Pathway (645338); Synthesis Of PIPs At The Late Endosome Membrane Pathway (645341)
ncbi summary :
This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
uniprot summary :
MTMR2: Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. Homooligomer and heterooligomer. Interacts with SBF1 and SBF2. interaction with SBF1 increases phosphatase activity. Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. Protein type: EC 3.1.3.95; Protein phosphatase, tyrosine (non-receptor); Cofactor and Vitamin Metabolism - riboflavin; EC 3.1.3.64; Phosphatase, lipid; Motility/polarity/chemotaxis; Carbohydrate Metabolism - fructose and mannose; Cofactor and Vitamin Metabolism - thiamine. Chromosomal Location of Human Ortholog: 11q22. Cellular Component: synaptic vesicle; early endosome membrane; axon; vacuolar membrane; dendrite; cytoplasm; dendritic spine; nucleus; cytosol. Molecular Function: protein binding; phosphatidylinositol-3-phosphatase activity; protein homodimerization activity; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity. Biological Process: myelin formation; negative regulation of myelination; inositol phosphate dephosphorylation; negative regulation of endocytosis; phospholipid metabolic process; phosphatidylinositol biosynthetic process; neuron development; phosphoinositide dephosphorylation; protein amino acid dephosphorylation; protein tetramerization; negative regulation of receptor internalization. Disease: Charcot-marie-tooth Disease, Type 4b1
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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