Human Sodium channel protein type 11 subunit alpha, SCN11A ELISA Kit | MyBioSource MBS9316032 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Human Sodium channel protein type 11 subunit alpha, SCN11A ELISA Kit

catalog :

MBS9316032

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9316032

products type :

ELISA Kit

products full name :

Human Sodium channel protein type 11 subunit alpha, SCN11A ELISA Kit

products short name :

[sodium channel, voltage-gated, type XI, alpha subunit]

products name syn :

[Human Sodium channel protein type 11 subunit alpha (SCN11A) ELISA kit; NAV1.9; NaN; SCN12A; SNS-2; sodium channel; voltage-gated; type XI; alpha; sodium channel; voltage-gated; type XI; alpha polypeptide; sodium channel; voltage-gated; type XII; alpha polypeptide; voltage; sodium channel; voltage-gated; type XI; alpha subunit]

other names :

[sodium channel protein type 11 subunit alpha; Sodium channel protein type 11 subunit alpha; sodium channel protein type 11 subunit alpha; sensory neuron sodium channel 2; peripheral nerve sodium channel 5; sodium channel protein type XI subunit alpha; voltage-gated sodium channel subunit alpha Nav1.9; sodium channel, voltage-gated, type XI, alpha polypeptide; sodium channel, voltage-gated, type XII, alpha polypeptide; sodium channel, voltage-gated, type XI, alpha subunit; Peripheral nerve sodium channel 5; PN5; Sensory neuron sodium channel 2; Sodium channel protein type XI subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.9; hNaN]

products gene name :

[SCN11A]

other gene names :

[SCN11A; SCN11A; NaN; PN5; FEPS3; HSAN7; SNS-2; NAV1.9; SCN12A; SCN12A; SNS2; PN5]

uniprot entry name :

SCNBA_HUMAN

reactivity :

Human

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Human Serum, Plasma Or Tissue Homogenates Samples. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of SCN10A (hereafter termed "analyte") in undiluted original Human serum, plasma or tissue homogenates samples. For other sample types please contact tech support to determine compatibility with this assay. This kit is not suitable for assaying non-biological sources of substances.

ncbi gi num :

564473389

ncbi acc num :

NP_001274152.1

ncbi gb acc num :

NM_001287223.1

uniprot acc num :

Q9UI33

ncbi mol weight :

204,922 Da

ncbi summary :

Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM, Apr 2004]

uniprot summary :

SCN11A: This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization. Belongs to the sodium channel (TC 1.A.1.10) family. Nav1.9/SCN11A subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, multi-pass; Channel, sodium; Membrane protein, integral. Chromosomal Location of Human Ortholog: 3p22.2. Cellular Component: voltage-gated sodium channel complex; plasma membrane. Molecular Function: voltage-gated sodium channel activity. Biological Process: response to drug; sodium ion transport; generation of action potential; regulation of sensory perception of pain. Disease: Neuropathy, Hereditary Sensory And Autonomic, Type Vii; Episodic Pain Syndrome, Familial, 3

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage