catalog number :
MBS931556
products type :
ELISA Kit
products full name :
Mouse Interleukin-18 receptor 1, IL18R1 ELISA Kit
products short name :
interleukin 18 receptor 1
products name syn :
Mouse Interleukin-18 receptor 1 (IL18R1) ELISA kit; CD218a; CDw218a; IL-1Rrp; IL18RA; IL1RRP; IL1 receptor-related protein; OTTHUMP00000161340; OTTHUMP00000203113; cytokine receptor; interleukin 18 receptor 1
other names :
interleukin-18 receptor 1 isoform a; Interleukin-18 receptor 1; interleukin-18 receptor 1; IL-18R1; IL-1Rrp; IL1R-rp; IL-18R-1; IL1 receptor-related protein; CD218 antigen-like family member A; interleukin 1 receptor related protein; interleukin 18 receptor 1; CD218 antigen-like family member A; IL1 receptor-related protein; IL-1Rrp; IL1R-rp; CD_antigen: CD218a
products gene name :
IL18R1
other gene names :
Il18r1; Il18r1; Il1rrp; Il18ralpha; IL-18R-1; IL-18R1; IL-1Rrp; IL1R-rp
uniprot entry name :
IL18R_MOUSE
specificity :
This assay has high sensitivity and excellent specificity for detection of Mouse IL18R1. No significant cross-reactivity or interference between Mouse IL18R1 and analogues was observed.
storage stability :
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
other info1 :
Samples: Serum, plasma, tissue homogenates. Assay Type: Sandwich. Detection Range: 15.6 pg/ml-1000 pg/ml. Sensitivity: 3.9 pg/ml
other info2 :
Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%. Three samples of known concentration were tested twenty times on one plate to assess. Inter-assay Precision (Precision between assays): CV% is less than 10%. Three samples of known concentration were tested in twenty assays to assess. Detection Wavelength: 450 nm. Sample Volume: 50-100ul
products description :
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for IL18R1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any IL18R1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for IL18R1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of IL18R1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
ncbi acc num :
NP_032391.1
ncbi gb acc num :
NM_008365.2
ncbi mol weight :
61,601 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway (83248); Cytokine-cytokine Receptor Interaction Pathway (460); Inflammatory Bowel Disease (IBD) Pathway (842778); Inflammatory Bowel Disease (IBD) Pathway (842797); TNF Signaling Pathway (812263); TNF Signaling Pathway (813210)
uniprot summary :
IL18R1: Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family. Protein type: Membrane protein, integral. Cellular Component: membrane; integral to membrane. Molecular Function: interleukin-18 receptor activity. Biological Process: positive regulation of interferon-gamma production; T-helper 1 cell differentiation; natural killer cell activation; positive regulation of NF-kappaB import into nucleus; signal transduction
size4 :
10x96-Strip-Wells