catalog number :
MBS9313140
products type :
ELISA Kit
products full name :
Human Neuroligin 1 (NLGN1) ELISA Kit
products short name :
[Neuroligin 1 (NLGN1)]
other names :
[neuroligin-1; Neuroligin-1; neuroligin-1; neuroligin 1]
products gene name :
[NLGN1]
other gene names :
[NLGN1; NLGN1; NL1; KIAA1070]
uniprot entry name :
NLGN1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: undiluted original Human body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 6.25ng/ml-200ng/mL. Sensitivity: 1.0ng/mL
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NLGN1 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_055747.1
ncbi gb acc num :
NM_014932.3
ncbi mol weight :
93,835 Da
ncbi pathways :
Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480)
ncbi summary :
This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008]
uniprot summary :
NLGN1: Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Belongs to the type-B carboxylesterase/lipase family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, integral. Chromosomal Location of Human Ortholog: 3q26.31. Cellular Component: filopodium tip; postsynaptic membrane; extracellular space; cell surface; integral to plasma membrane; dendrite; excitatory synapse; synapse; cell junction; N-methyl-D-aspartate selective glutamate receptor complex; external side of plasma membrane. Molecular Function: protein dimerization activity; neurexin binding; receptor activity; cell adhesion molecule binding; PDZ domain binding. Biological Process: positive regulation of filopodium formation; regulation of synaptic transmission; nervous system development; regulation of neuron differentiation; metabolic process; positive regulation of synaptic transmission, GABAergic; rhythmic process; neurological control of breathing; positive regulation of synaptic transmission, glutamatergic; heterophilic cell adhesion; positive regulation of synaptogenesis; establishment of protein localization; synaptogenesis; cytoskeletal matrix organization at active zone; calcium-dependent cell-cell adhesion; protein heterotetramerization; neuron adhesion; synaptic vesicle targeting; protein homooligomerization; protein targeting
size4 :
10x96-Strip-Wells