catalog number :
MBS9313066
products type :
ELISA Kit
products full name :
Human Phosphodiesterase 7A (PDE7A) ELISA Kit
products short name :
[Phosphodiesterase 7A (PDE7A)]
other names :
[phosphodiesterase 7A; Phosphodiesterase 7A; high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A; TM22; phosphodiesterase isozyme 7; phosphodiesterase 7A]
products gene name :
[PDE7A]
other gene names :
[PDE7A; PDE7A; HCP1; PDE7]
uniprot entry name :
Q7Z7I0_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Assay Type: Sandwich. Detection Range: 0.25 ng/ml - 8 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PDE7A (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
CAD29836.1
ncbi mol weight :
4,955 Da
ncbi pathways :
G Protein Signaling Pathways (198849); G Alpha (s) Signalling Events Pathway (119549); GPCR Downstream Signaling Pathway (119548); Morphine Addiction Pathway (552665); Morphine Addiction Pathway (554808); Purine Metabolism Pathway (82944); Purine Metabolism Pathway (307); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356)
ncbi summary :
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2011]
uniprot summary :
PDE7A: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction. Belongs to the cyclic nucleotide phosphodiesterase family. PDE7 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Nucleotide Metabolism - purine; Phosphodiesterase; EC 3.1.4.53. Chromosomal Location of Human Ortholog: 8q13. Cellular Component: cytosol. Molecular Function: 3 ,5 -cyclic-AMP phosphodiesterase activity; metal ion binding. Biological Process: cAMP catabolic process; signal transduction
size4 :
10x96-Strip-Wells