catalog number :
MBS9313008
products type :
ELISA Kit
products full name :
Human Parvin Beta (PARVb) ELISA Kit
products short name :
[Parvin Beta (PARVb)]
other names :
[parvin, beta, isoform CRA_d; Beta-parvin; beta-parvin; affixin; parvin, beta; Affixin]
products gene name :
[PARVb]
other gene names :
[PARVB; PARVB; CGI-56]
uniprot entry name :
PARVB_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Mouse Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.25ng/ml-8ng/ml. Sensitivity: 0.1ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) are less than 15%. Inter-assay Precision: Inter-assay CV (?) are less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of PARP9 (hereafter termed "analyte") in undiluted original Mouse body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
EAW73331.1
ncbi mol weight :
41,714 Da
ncbi pathways :
Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-extracellular Matrix Interactions Pathway (160967); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); Regulation Of Cytoskeletal Remodeling And Cell Spreading By IPP Complex Components Pathway (160969)
ncbi summary :
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
uniprot summary :
PARVB: Probably plays a role in the regulation of cell adhesion and cytoskeleton organization. Belongs to the parvin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Actin-binding; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 22q13.2-q13.33. Cellular Component: cytoskeleton; focal adhesion; lamellipodium; plasma membrane; Z disc; cytosol. Molecular Function: protein binding; actin binding. Biological Process: lamellipodium biogenesis; actin cytoskeleton reorganization; cell projection biogenesis; cell adhesion
size4 :
10x96-Strip-Wells