This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human Obscurin (OBSCN) ELISA Kit
catalog :
MBS9312359
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS9312359
products type :
ELISA Kit
products full name :
Human Obscurin (OBSCN) ELISA Kit
products short name :
[Obscurin (OBSCN)]
other names :
[obscurin; Obscurin; obscurin; obscurin-MLCK; obscurin, myosin light chain kinase; obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; Obscurin-RhoGEF; Obscurin-myosin light chain kinase]
products gene name :
[OBSCN]
other gene names :
[OBSCN; OBSCN; UNC89; ARHGEF30; KIAA1556; KIAA1639; Obscurin-MLCK]
uniprot entry name :
OBSCN_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of OBSCN (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
15026974
ncbi acc num :
CAC44768.1
uniprot acc num :
Q5VST9
ncbi mol weight :
868,484 Da
ncbi pathways :
Cell Death Signalling Via NRAGE, NRIF And NADE Pathway (106443); G Alpha (12/13) Signalling Events Pathway (106041); GPCR Downstream Signaling Pathway (119548); NRAGE Signals Death Through JNK Pathway (106444); Regulation Of RhoA Activity Pathway (138070); Rho GTPase Cycle Pathway (106503); Signal Transduction Pathway (477114); Signaling By GPCR Pathway (106356); Signaling By Rho GTPases Pathway (106502); Signalling By NGF Pathway (106439)
ncbi summary :
The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
uniprot summary :
OBSCN: a Ca(2+)/calmodulin-dependent protein kinase of the Trio family. A giant protein with one Rho GEF domain, one PH domain and two kinase domains. Expressed in skeletal and cardiac muscle, concentrating around Z-disks and M-lines of striated muscle. Binds ankyrin 1 interacts with sarcomeric myosin. May play a critical role in its ability to assemble into A bands in striated muscle. Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CAMK; Kinase, protein; EC 2.7.11.1; CAMK group; Trio family. Chromosomal Location of Human Ortholog: 1q42.13. Cellular Component: myofibril; M band; Z disc; cytosol. Molecular Function: calmodulin binding; protein serine/threonine kinase activity; protein binding; Rho guanyl-nucleotide exchange factor activity; structural constituent of muscle; metal ion binding; titin binding; ankyrin binding; ATP binding. Biological Process: regulation of small GTPase mediated signal transduction; nerve growth factor receptor signaling pathway; positive regulation of apoptosis; multicellular organismal development; small GTPase mediated signal transduction; sarcomere organization; protein amino acid phosphorylation
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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