catalog number :
MBS9312179
products type :
ELISA Kit
products full name :
Human Fibroblast Growth Factor-15 (FGF-15) ELISA Kit
products short name :
[Fibroblast Growth Factor-15 (FGF-15)]
other names :
[fibroblast growth factor 15; Fibroblast growth factor 15; fibroblast growth factor 15; FGF-15; fibroblast growth factor 15]
products gene name :
[FGF-15]
other gene names :
[Fgf15; Fgf15; FGF19; FGF-15]
uniprot entry name :
FGF15_MOUSE
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 62.5 pg/ml - 2000 pg/ml. Sensitivity: 10 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FGF15 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_032029.1
ncbi gb acc num :
NM_008003.2
ncbi mol weight :
25,236 Da
ncbi pathways :
Adaptive Immune System Pathway (819568); Constitutive PI3K/AKT Signaling In Cancer Pathway (819551); DAP12 Interactions Pathway (819675); DAP12 Signaling Pathway (819676); Disease Pathway (819462); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (819582); Downstream Signal Transduction Pathway (819799); Downstream Signaling Of Activated FGFR Pathway (819508); ESC Pluripotency Pathways (198374); FGFR Ligand Binding And Activation Pathway (819494)
uniprot summary :
FGF19: Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. Belongs to the heparin-binding growth factors family. Protein type: Cytokine; Cell development/differentiation; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted. Cellular Component: extracellular region. Molecular Function: protein binding; growth factor activity; fibroblast growth factor receptor binding; receptor binding. Biological Process: positive regulation of glucose import; fibroblast growth factor receptor signaling pathway; heart development; positive regulation of cell proliferation; positive regulation of JNK cascade; positive regulation of protein amino acid phosphorylation; neural crest cell migration
size4 :
10x96-Strip-Wells