This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
ELISA/assay
product name :
Human T-Cell Leukemia/Lymphoma Protein 1A (TCL1A) ELISA Kit
catalog :
MBS9312008
quantity :
48-Strip-Wells
price :
470 USD
product information
catalog number :
MBS9312008
products type :
ELISA Kit
products full name :
Human T-Cell Leukemia/Lymphoma Protein 1A (TCL1A) ELISA Kit
products short name :
[T-Cell Leukemia/Lymphoma Protein 1A (TCL1A)]
other names :
[T-cell leukemia/lymphoma protein 1A; T-cell leukemia/lymphoma protein 1A; T-cell leukemia/lymphoma protein 1A; oncogene TCL1; oncogene TCL-1; protein p14 TCL1; T-cell lymphoma-1; T-cell leukemia/lymphoma 1A; Oncogene TCL-1; Oncogene TCL1; Protein p14 TCL1]
products gene name :
[TCL1A]
other gene names :
[TCL1A; TCL1A; TCL1; TCL1; Oncogene TCL1]
uniprot entry name :
TCL1A_HUMAN
reactivity :
Human
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 3.12 ng/ml - 100 ng/ml. Sensitivity: 1.0 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TCL1A (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi gi num :
148922879
ncbi acc num :
NP_001092195.1
ncbi gb acc num :
NM_001098725.1
uniprot acc num :
P56279
ncbi mol weight :
13,460 Da
ncbi pathways :
PI3K-Akt Signaling Pathway (692234); PI3K-Akt Signaling Pathway (692979)
ncbi summary :
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
uniprot summary :
TCL1A: Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival. Homodimer. Interacts with AKT1, AKT2 and AKT3 (via PH domain). Interacts with PNPT1; the interaction has no effect on PNPT1 exonuclease activity. Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation. Belongs to the TCL1 family. Protein type: Protein kinase, regulatory subunit; Oncoprotein. Chromosomal Location of Human Ortholog: 14q32.1. Cellular Component: pronucleus; endoplasmic reticulum; cell cortex. Molecular Function: protein binding. Biological Process: multicellular organismal development; stem cell maintenance
size1 :
48-Strip-Wells
price1 :
470 USD
size2 :
96-Strip-Wells
price2 :
680
size3 :
5x96-Strip-Wells
price3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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