catalog number :
MBS9311994
products type :
ELISA Kit
products full name :
Mouse Forkhead Box Protein M1 (FOXM1) ELISA Kit
products short name :
Forkhead Box Protein M1 (FOXM1)
other names :
forkhead box protein M1 isoform 5; Forkhead box protein M1; forkhead box protein M1; M-phase phosphoprotein 2; HNF-3/fork-head homolog 11; transcription factor Trident; MPM-2 reactive phosphoprotein 2; forkhead-related protein FKHL16; winged-helix factor from INS-1 cells; Forkhead, drosophila, homolog-like 16; hepatocyte nuclear factor 3 forkhead homolog 11; forkhead box M1; Forkhead-related protein FKHL16; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HNF-3/fork-head homolog 11; M-phase phosphoprotein 2; MPM-2 reactive phosphoprotein 2; Transcription factor Trident; Winged-helix factor from INS-1 cells
products gene name :
FOXM1
other gene names :
FOXM1; FOXM1; MPP2; TGT3; HFH11; HNF-3; INS-1; MPP-2; PIG29; FKHL16; FOXM1B; HFH-11; TRIDENT; MPHOSPH2; FKHL16; HFH11; MPP2; WIN; HFH-11
uniprot entry name :
FOXM1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of FOXM1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001230018.1
ncbi gb acc num :
NM_001243089.1
ncbi mol weight :
84,283 Da
ncbi pathways :
FOXM1 Transcription Factor Network Pathway (137935); SIDS Susceptibility Pathways (198901)
ncbi summary :
The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
uniprot summary :
FOXM1: a transcriptional activator factor. Contains 1 fork-head domain. May play a role in the control of cell proliferation. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Phosphorylated in M (mitotic) phase. Three splice variant isoforms have been described. Isoform 1 and isoform 2 appear to be the only activators of gene transcription. Isoform 3, found in rat, does not seem to exist in human. Protein type: DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: nucleoplasm; cytoplasm. Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; protein kinase binding; transcription factor activity. Biological Process: regulation of Ras protein signal transduction; transcription from RNA polymerase II promoter; regulation of cell cycle; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; DNA repair; negative regulation of stress-activated MAPK cascade; liver development; cell cycle; regulation of cell proliferation; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; regulation of cell growth; mitotic cell cycle; G2/M transition of mitotic cell cycle; vasculogenesis; negative regulation of transcription, DNA-dependent