catalog number :
MBS9311880
products type :
ELISA Kit
products full name :
Human Prohibitin 2 (PHB2) ELISA Kit
products short name :
Prohibitin 2 (PHB2)
other names :
prohibitin-2 isoform 3; Prohibitin-2; prohibitin-2; D-prohibitin; B-cell associated protein; repressor of estrogen receptor activity; B-cell receptor-associated protein BAP37; prohibitin 2; B-cell receptor-associated protein BAP37; D-prohibitin; Repressor of estrogen receptor activity
products gene name :
PHB2
other gene names :
PHB2; PHB2; BAP; REA; p22; Bap37; BCAP37; PNAS-141; BAP; REA
uniprot entry name :
PHB2_HUMAN
storage stability :
Store all reagents at 2-8 degree C
ncbi acc num :
NP_001254629.1
ncbi gb acc num :
NM_001267700.1
ncbi mol weight :
33,296 Da
uniprot summary :
BAP37: a protein of the band 7 family. This family includes the prohibitins, cytoplasmic anti-proliferative proteins and stomatin, an erythrocyte membrane protein. A repressor of estrogen receptor (ER) activity. Reverses steroid receptor coactivator 1 enhancement of ER activity. May play a role in determining the sensitivity of estrogen target cells to antiestrogen and estrogen therapy. Protein type: Nuclear receptor co-regulator; Mitochondrial; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: nuclear matrix; protein complex; mitochondrion; mitochondrial inner membrane; nucleus. Molecular Function: protein binding; estrogen receptor binding. Biological Process: transcription, DNA-dependent; negative regulation of transcription, DNA-dependent; negative regulation of mammary gland epithelial cell proliferation; negative regulation of estrogen receptor signaling pathway