catalog number :
MBS9311324
products type :
ELISA Kit
products full name :
Human Cyclin B3 (CCNB3) ELISA Kit
products short name :
[Cyclin B3 (CCNB3)]
other names :
[cyclin B3; G2/mitotic-specific cyclin-B3; G2/mitotic-specific cyclin-B3; cyclin B3]
products gene name :
[CCNB3]
other gene names :
[CCNB3; CCNB3; CYCB3]
uniprot entry name :
CCNB3_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Body fluids, tissue homogenates, secretions or feces samples. Assay Type: Quantitative Sandwich. Detection Range: 31.2 pg/ml - 1000 pg/ml. Sensitivity: 5.0 pg/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CCNB3 (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
CAC94915.1
ncbi mol weight :
157,916 Da
ncbi pathways :
Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); DNA Damage Response Pathway (198788); Progesterone-mediated Oocyte Maturation Pathway (119304); Progesterone-mediated Oocyte Maturation Pathway (503); P53 Signaling Pathway (83055); P53 Signaling Pathway (465)
ncbi summary :
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
uniprot summary :
CCNB3: Cyclins are positive regulatory subunits of the cyclin- dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle, notably via their destruction during cell division. Its tissue specificity suggest that it may be required during early meiotic prophase I. Belongs to the cyclin family. Cyclin AB subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Cell cycle regulation. Chromosomal Location of Human Ortholog: Xp11. Cellular Component: nucleoplasm. Molecular Function: protein binding; protein kinase binding. Biological Process: meiotic cell cycle; cell division; regulation of G2/M transition of mitotic cell cycle; regulation of cyclin-dependent protein kinase activity
size4 :
10x96-Strip-Wells