catalog number :
MBS9310900
products type :
ELISA Kit
products full name :
Pig tissue factor pathway inhibitor, TFPI ELISA Kit
products short name :
[tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)]
products name syn :
[Pig tissue factor pathway inhibitor (TFPI) ELISA kit; EPI; LACI; TFI; TFPI1; OTTHUMP00000163472; OTTHUMP00000205431; convertin; extrinsic pathway inhibitor; lipoprotein-associated coagulation inhibitor; tissue factor pathway inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)]
other names :
[tissue factor pathway inhibitor isoform b; Tissue factor pathway inhibitor; tissue factor pathway inhibitor; anti-convertin; extrinsic pathway inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor); Extrinsic pathway inhibitor; EPI; Lipoprotein-associated coagulation inhibitor; LACI]
products gene name :
[TFPI]
other gene names :
[TFPI; TFPI; EPI; TFI; LACI; TFPI1; LACI; TFPI1; TFPI; EPI; LACI]
uniprot entry name :
TFPI1_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Quantitative Sandwich. Detection Range: 31.2 ng/ml - 1000 ng/ml. Sensitivity: 5.0 ng/ml
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TFPI (hereafter termed "analyte") in undiluted original Porcine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_001027452.1
ncbi gb acc num :
NM_001032281.2
ncbi mol weight :
35,015 Da
ncbi pathways :
Complement And Coagulation Cascades Pathway (198880); Complement And Coagulation Cascades Pathway (83073); Complement And Coagulation Cascades Pathway (484); Extrinsic Pathway (106058); Formation Of Fibrin Clot (Clotting Cascade) Pathway (106057); Hemostasis Pathway (106028); Integrated Breast Cancer Pathway (219801); Syndecan-4-mediated Signaling Events Pathway (138064)
ncbi summary :
This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008]
uniprot summary :
TFPI: Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Inhibitor; Membrane protein, GPI anchor; Secreted, signal peptide; Secreted. Chromosomal Location of Human Ortholog: 2q32. Cellular Component: extracellular space; cell surface; endoplasmic reticulum; plasma membrane; extracellular region. Molecular Function: serine-type endopeptidase inhibitor activity; endopeptidase inhibitor activity. Biological Process: blood coagulation, extrinsic pathway; blood coagulation
size4 :
10x96-Strip-Wells