catalog number :
MBS9310896
products type :
ELISA Kit
products full name :
Rat Cytochrome P450 3A2, Cyp3a2 ELISA Kit
products short name :
[Cytochrome P450 3A2 (Cyp3a2)]
products name syn :
[Rat Cytochrome P450 3A2 (Cyp3a2) ELISA kit; Recommended name: Cytochrome P450 3A2 EC=1.14.14.1 Alternative name (s) : CYPIIIA2 Cytochrome P450-PCN2 Cytochrome P450/6-beta-A Testosterone 6-beta-hydroxylase Name:Cyp3a2 Synonyms:Cyp3a-2; Cyp3a11; Cytochrome P450 3A2 (Cyp3a2)]
other names :
[cytochrome P450 3A2; Cytochrome P450 3A2; cytochrome P450 3A2; CYPIIIA2; P450-PCN2; P450/6-beta-A; cytochrome P450-PCN2; cytochrome P450/6-beta-A; testosterone 6-beta-hydroxylase; cytochrome P450, family 3, subfamily a, polypeptide 11; cytochrome P450, family 3, subfamily a, polypeptide 2; CYPIIIA2; Cytochrome P450-PCN2; Cytochrome P450/6-beta-A; Testosterone 6-beta-hydroxylase]
products gene name :
[Cyp3a2]
other gene names :
[Cyp3a2; Cyp3a2; Cyp3a11; Cyp3a-2; Cyp3a11]
uniprot entry name :
CP3A2_RAT
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CYP3A2 (hereafter termed "analyte") in undiluted original Rat body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_695224.2
ncbi gb acc num :
NM_153312.2
ncbi mol weight :
57,732 Da
ncbi pathways :
Chemical Carcinogenesis Pathway (673233); Chemical Carcinogenesis Pathway (673237); Fatty Acid Omega Oxidation Pathway (198442); Linoleic Acid Metabolism Pathway (83384); Linoleic Acid Metabolism Pathway (367); Retinol Metabolism Pathway (83412); Retinol Metabolism Pathway (406); Steroid Hormone Biosynthesis Pathway (83333); Steroid Hormone Biosynthesis Pathway (301)
ncbi summary :
catalyzes the conversion of testosterone to 6-beta-hydroxytestosterone [RGD, Feb 2006]
uniprot summary :
CYP3A4: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1 -hydroxylation and midazolam 4- hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2- exo-monooxygenase. The enzyme also hydroxylates etoposide. Belongs to the cytochrome P450 family. Protein type: Endoplasmic reticulum; Membrane protein, peripheral; Oxidoreductase; Cell surface; Demethylase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Lipid Metabolism - linoleic acid; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - other enzymes; Membrane protein, integral; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.14.14.1. Cellular Component: endoplasmic reticulum membrane; cytoplasm. Molecular Function: enzyme binding; iron ion binding; heme binding; oxidoreductase activity; steroid hydroxylase activity; monooxygenase activity; steroid binding; testosterone 6-beta-hydroxylase activity; demethylase activity; vitamin D3 25-hydroxylase activity. Biological Process: steroid metabolic process; drug catabolic process; exogenous drug catabolic process; monoterpenoid metabolic process; alkaloid catabolic process; heterocycle metabolic process; drug metabolic process; steroid catabolic process
size4 :
10x96-Strip-Wells