ELISA/assay

Human heterogeneous nuclear ribonucleoprotein C, hnRNP C ELISA Kit

MBS9310760

48-Strip-Wells

435 USD

ELISA Kit

Human heterogeneous nuclear ribonucleoprotein C, hnRNP C ELISA Kit

heterogeneous nuclear ribonucleoprotein C (C1/C2)

Human heterogeneous nuclear ribonucleoprotein C (hnRNP C) ELISA Kit; C1; C2; HNRNP; HNRPC; MGC104306; MGC105117; MGC117353; MGC131677; SNRPC; heterogeneous nuclear ribonucleoprotein C; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2; heterogeneous nuclear ribonucleoprotein C (C1/C2)

heterogeneous nuclear ribonucleoproteins C1/C2 isoform a; Heterogeneous nuclear ribonucleoproteins C1/C2; heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2; nuclear ribonucleoprotein particle C1 protein; nuclear ribonucleoprotein particle C2 protein; heterogeneous nuclear ribonucleoprotein C (C1/C2)

HNRNPC

HNRNPC; HNRNPC; C1; C2; HNRNP; HNRPC; SNRPC; HNRPC; hnRNP C1/C2

HNRPC_HUMAN

Human

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 0.625 ng/ml - 20 ng/ml. Sensitivity: 0.1 ng/ml.

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HNRNPC (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.

117190192

NP_001070910.1

NM_001077442.1

P07910

33,670 Da

Gene Expression Pathway (105937); Processing Of Capped Intron-Containing Pre-mRNA Pathway (160950); Regulation Of Telomerase Pathway (137987); Spliceosome Pathway (125136); Spliceosome Pathway (124832); MRNA Splicing Pathway (105951); MRNA Splicing - Major Pathway (105952); MRNA Processing Pathway (198843)

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene can act as a tetramer and is involved in the assembly of 40S hnRNP particles. Multiple transcript variants encoding at least two different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

hnRNP C1/C2: a heterogeneous nuclear ribonucleoprotein. May play a role in ribonucleosome assembly by neutralizing basic proteins such as A and B core hnRNP. Contains 1 RNA recognition motif (RRM) domain. Two alternatively spliced isoforms have been described. Protein type: RNA-binding; RNA splicing; Spliceosome. Chromosomal Location of Human Ortholog: 14q11.2. Cellular Component: nucleoplasm; spliceosome; protein complex; membrane; nuclear chromatin; cytosol; nucleus. Molecular Function: identical protein binding; protein binding; nucleosomal DNA binding; mRNA 3 -UTR binding; RNA binding; nucleotide binding; poly(U) binding. Biological Process: osteoblast differentiation; nuclear mRNA splicing, via spliceosome; RNA splicing; ATP-dependent chromatin remodeling; gene expression

48-Strip-Wells

435 USD

96-Strip-Wells

600