catalog number :
MBS9310690
products type :
ELISA Kit
products full name :
Human Heat Shock Protein 22 (HSP-22) ELISA Kit
products short name :
[Heat Shock Protein 22 (HSP-22)]
products name syn :
[heat shock 22kDa protein 8; CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22; E2-induced gene 1 heat shock 27kDa protein 8 heat shock protein beta-8 protein kinase H11 small stress protein-like protein HSP22]
other names :
[heat shock protein beta-8; Heat shock protein beta-8; heat shock protein beta-8; protein kinase H11; alpha-crystallin C chain; E2-induced gene 1 protein; heat shock 27kDa protein 8; small stress protein-like protein HSP22; heat shock 22kDa protein 8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22]
products gene name :
[HSPB8]
other gene names :
[HSPB8; HSPB8; H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22; CRYAC; E2IG1; HSP22; HspB8]
uniprot entry name :
HSPB8_HUMAN
specificity :
No significant cross-reactivity or interference between this analyte and analogues is observed.
storage stability :
Store all reagents at 2-8 degree C
other info1 :
Samples: Human Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 3.12ng/ml-100ng/ml. Sensitivity: 1.0ng/ml.
other info2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.
products description :
Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of HSP17 (hereafter termed "analyte") in undiluted original Human body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.
ncbi acc num :
NP_055180.1
ncbi gb acc num :
NM_014365.2
ncbi mol weight :
21,604 Da
ncbi summary :
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
uniprot summary :
HSPB8: Displays temperature-dependent chaperone activity. Monomer. Interacts with HSPB1. Interacts with DNAJB6. By 17-beta-estradiol. Predominantly expressed in skeletal muscle and heart. Belongs to the small heat shock protein (HSP20) family. Protein type: Heat shock protein. Chromosomal Location of Human Ortholog: 12q24.23. Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; intracellular; nucleus. Molecular Function: identical protein binding; protein binding; protein kinase activity. Disease: Charcot-marie-tooth Disease, Axonal, Type 2l; Neuronopathy, Distal Hereditary Motor, Type Iia
size4 :
10x96-Strip-Wells